Preprint Review Version 2 Preserved in Portico This version is not peer-reviewed

Prevalence of COVID-19: A Look behind the Scenes

Version 1 : Received: 10 April 2020 / Approved: 12 April 2020 / Online: 12 April 2020 (04:30:07 CEST)
Version 2 : Received: 14 April 2020 / Approved: 15 April 2020 / Online: 15 April 2020 (08:25:18 CEST)

How to cite: Haj Bloukh, S.; Shaikh, A. A.; Pathan, H. M.; Edis, Z. Prevalence of COVID-19: A Look behind the Scenes. Preprints 2020, 2020040179. Haj Bloukh, S.; Shaikh, A. A.; Pathan, H. M.; Edis, Z. Prevalence of COVID-19: A Look behind the Scenes. Preprints 2020, 2020040179.


Mankind faces a coronavirus pandemic originating from a seafood market in Wuhan, China since December 2019. The pathogen was named novel coronavirus (n-CoV) and bats are the identified key reservoir. The coronavirus disease 2019 (COVID-19) quickly spread over China across the globe, turned into a pandemic with exponentially increasing numbers of cases and significant mortality rate. China reacted with lockdowns and strict control measurements to prevent spreading the virus. The treatment of severe cases was hampered by lack of specific vaccines. Vaccine-development and production is a painstaking process and can only be enforced by international cooperation. Different supportive treatment options surfaced due to combinations of antiviral agents with antibiotic drugs. Elderly, male, immune-suppressed patients with co-morbidities showed a high mortality rate. Health literacy, strong immune system, adequate serum 25-hydroxyvitamin D (25(OH)D) concentrations and healthy life style choices can support fast recovery. Antibiotic resistance needs to be addressed by development of new generation antimicrobials against nosocomial infections in preparation for future outbreaks. Plant-biosynthesis of nanomaterials and antiseptics may help in prevention and recovery rate. Prevalence of COVID-19 maybe inversely related to BCG vaccination, endemicity of malaria, humidy and temperature but directly with latitude. Recommendations to prevent the spread of COVID-19 should be followed strictly.


COVID-19; SARS-CoV-2; human coronavirus; control; vitamin D; antibiotic resistance; antimicrobial agents; BCG; malaria; climate; latitude


Biology and Life Sciences, Virology

Comments (2)

Comment 1
Received: 15 April 2020
Commenter: Zehra Edis
Commenter's Conflict of Interests: Author
Comment: We added a conclusion and changed the title by removing the two countries.
We submitted to the journal Pathogens last night.
+ Respond to this comment
Comment 2
Received: 21 April 2020
Commenter: Ann Kelly
The commenter has declared there is no conflict of interests.
Comment: I thought it was a really interesting and well researched article. I thought the part about Vit D and Iron were interesting and the list of interventions each country did was interesting. Add in Australia and New Zealand?

The word fastly does not occur in the English language and should be replaced with quickly.
+ Respond to this comment

We encourage comments and feedback from a broad range of readers. See criteria for comments and our Diversity statement.

Leave a public comment
Send a private comment to the author(s)
* All users must log in before leaving a comment
Views 0
Downloads 0
Comments 2
Metrics 0

Notify me about updates to this article or when a peer-reviewed version is published.
We use cookies on our website to ensure you get the best experience.
Read more about our cookies here.