Version 1
: Received: 12 March 2020 / Approved: 12 March 2020 / Online: 12 March 2020 (15:02:49 CET)
How to cite:
D'Annessa, I.; Marchetti, F.; Colombo, G. Binding Epitopes of 2019-nCoV Proteins for Perspective Diagnostic and Therapeutic Applications: Insights from Computational Approaches. Preprints2020, 2020030221. https://doi.org/10.20944/preprints202003.0221.v1
D'Annessa, I.; Marchetti, F.; Colombo, G. Binding Epitopes of 2019-nCoV Proteins for Perspective Diagnostic and Therapeutic Applications: Insights from Computational Approaches. Preprints 2020, 2020030221. https://doi.org/10.20944/preprints202003.0221.v1
D'Annessa, I.; Marchetti, F.; Colombo, G. Binding Epitopes of 2019-nCoV Proteins for Perspective Diagnostic and Therapeutic Applications: Insights from Computational Approaches. Preprints2020, 2020030221. https://doi.org/10.20944/preprints202003.0221.v1
APA Style
D'Annessa, I., Marchetti, F., & Colombo, G. (2020). Binding Epitopes of 2019-nCoV Proteins for Perspective Diagnostic and Therapeutic Applications: Insights from Computational Approaches. Preprints. https://doi.org/10.20944/preprints202003.0221.v1
Chicago/Turabian Style
D'Annessa, I., Filippo Marchetti and Giorgio Colombo. 2020 "Binding Epitopes of 2019-nCoV Proteins for Perspective Diagnostic and Therapeutic Applications: Insights from Computational Approaches" Preprints. https://doi.org/10.20944/preprints202003.0221.v1
Abstract
The appearance of the novel betacoronavirus 2019-nCoV represents a major threat to human health, and its diffusion around the world is predicted to have dramatic economic consequences. The knowledge of the 3D structures of 2019-nCoV proteins can facilitate the development of diagnostic and therapeutic molecules. Herein, we apply our energy-based method for the prediction of potential epitopes on viral proteins to design peptide-based molecules that can subsequently be used in diagnostic and therapeutic applications. We discuss these aspects in the paper.The designs have not been tested. Our aim is to share information that can be useful in the development of novel biomolecules with potential interesting activities against 2019-nCoV.
Medicine and Pharmacology, Medicine and Pharmacology
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.