Preprint Review Version 1 This version is not peer-reviewed

Primary Cutaneous Anaplastic Large Cell Lymphoma (pcALCL) in Elderly, the Importance of a Sport Activity Training

Version 1 : Received: 28 December 2019 / Approved: 30 December 2019 / Online: 30 December 2019 (05:43:39 CET)

How to cite: Sica, A.; Vitiello, P.; Ronchi, A.; Casale, B.; Calogero, A.; Sagnelli, E.; Costa Nachtigal, G.; Troiani, T.; Franco, R.; Argenziano, G.; Moscarella, E.; Sagnelli, C. Primary Cutaneous Anaplastic Large Cell Lymphoma (pcALCL) in Elderly, the Importance of a Sport Activity Training. Preprints 2019, 2019120393 (doi: 10.20944/preprints201912.0393.v1). Sica, A.; Vitiello, P.; Ronchi, A.; Casale, B.; Calogero, A.; Sagnelli, E.; Costa Nachtigal, G.; Troiani, T.; Franco, R.; Argenziano, G.; Moscarella, E.; Sagnelli, C. Primary Cutaneous Anaplastic Large Cell Lymphoma (pcALCL) in Elderly, the Importance of a Sport Activity Training. Preprints 2019, 2019120393 (doi: 10.20944/preprints201912.0393.v1).

Abstract

PcALCL mainly concerns elderly patients. It is a large CD30+ T-cell neoplasm composed of large cells with anaplastic, pleomorphic or immunoblastic morphology, with exclusively cutaneous onset and localization. The clinical course of pcALCL is predominantly indolent. Most elderly patients with lymphoma tend to have a sedentary lifestyle, which has a negative effect on their quality of life (QoL) and on their survival. Several studies indicate that exercise has a positive impact on QoL because it reduces peak oxygen consumption, improves physical capacity, increases self-esteem, reduces accumulated stress and promotes relaxation. Therefore, particularly in indolent lymphomas, it is necessary to indicate a program of physical activity to be practiced systematically. The complete surgical excision and local radiotherapy are the first line gold standard in pcALCL with solitary lesion.

Subject Areas

cutaneous lymphoma in elderly; skin tumors; T-cell lymphomas; sport activity training

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