Version 1
: Received: 23 December 2019 / Approved: 24 December 2019 / Online: 24 December 2019 (10:59:14 CET)
How to cite:
Yang, J.; Wang, C.; Huang, K.; Zhang, M.; Wang, J.; Pan, X. Compound Lactobacillus sp. Administration Ameliorates Stress and Body Growth Through Gut Microbiota Optimization on Piglet Model. Preprints2019, 2019120315. https://doi.org/10.20944/preprints201912.0315.v1
Yang, J.; Wang, C.; Huang, K.; Zhang, M.; Wang, J.; Pan, X. Compound Lactobacillus sp. Administration Ameliorates Stress and Body Growth Through Gut Microbiota Optimization on Piglet Model. Preprints 2019, 2019120315. https://doi.org/10.20944/preprints201912.0315.v1
Yang, J.; Wang, C.; Huang, K.; Zhang, M.; Wang, J.; Pan, X. Compound Lactobacillus sp. Administration Ameliorates Stress and Body Growth Through Gut Microbiota Optimization on Piglet Model. Preprints2019, 2019120315. https://doi.org/10.20944/preprints201912.0315.v1
APA Style
Yang, J., Wang, C., Huang, K., Zhang, M., Wang, J., & Pan, X. (2019). Compound Lactobacillus sp. Administration Ameliorates Stress and Body Growth Through Gut Microbiota Optimization on Piglet Model. Preprints. https://doi.org/10.20944/preprints201912.0315.v1
Chicago/Turabian Style
Yang, J., Jing Wang and Xiaocheng Pan. 2019 "Compound Lactobacillus sp. Administration Ameliorates Stress and Body Growth Through Gut Microbiota Optimization on Piglet Model" Preprints. https://doi.org/10.20944/preprints201912.0315.v1
Abstract
The composition of bacteria in the gastrointestinal tract of piglets is easily affected by environmental changes, particularly during the weaning period. Compound strains of Lactobacillus reuteri and Lactobacillus salivarius were supplemented to piglets during pre- and post-weaning to determine their effects in improving the growth performance and ameliorating the diarrhea rate and stress caused by antioxidation in piglets. A larger number of L. reuteri and L. salivarius colonized the distal segment of the ileum and the total numbers of Lactobacillus spp. and Bifidobacterium were higher in the ileal mucous membrane and cecal lumen with probiotics supplementation. The numbers of antioxidative and immune molecules were increased in the plasma following compound bacteria (CL) supplementation, whereas cortisol and endotoxin levels were lower and growth hormone and insulin-like growth factor 1 were higher. Spearman’s and KEGG analysis of the bacterial operational taxonomic unit and antioxidative and immune indices and metabolic genes indicated that the body growth modulation by CL supplementation could be attributed to optimization of the intestinal bacterial composition. Collectively, these results suggest that supplementation with CL could reduce stress and improve the growth performance of piglets during weaning by optimizing the intestinal bacterial composition.
Keywords
Lactobacillus; piglet; weaning; gut microbiota; growth enhancement.
Subject
Biology and Life Sciences, Agricultural Science and Agronomy
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
