Yamaguchi, K.; Kuraku, S. Unbiasing Genome-Based Analyses of Selection: An Example Using Iconic Shark Species. Frontiers in Marine Science, 2021, 8. https://doi.org/10.3389/fmars.2021.573853.
Yamaguchi, K.; Kuraku, S. Unbiasing Genome-Based Analyses of Selection: An Example Using Iconic Shark Species. Frontiers in Marine Science, 2021, 8. https://doi.org/10.3389/fmars.2021.573853.
Yamaguchi, K.; Kuraku, S. Unbiasing Genome-Based Analyses of Selection: An Example Using Iconic Shark Species. Frontiers in Marine Science, 2021, 8. https://doi.org/10.3389/fmars.2021.573853.
Yamaguchi, K.; Kuraku, S. Unbiasing Genome-Based Analyses of Selection: An Example Using Iconic Shark Species. Frontiers in Marine Science, 2021, 8. https://doi.org/10.3389/fmars.2021.573853.
Abstract
A previous study involving whole genome sequencing of the white shark suggested unique molecular evolution accounting for gigantism and the enhanced longevity of sharks including positive selection of dozens of protein-coding genes potentially involved in genome stability. We performed a reanalysis on some of the genes and identified serious flaws in their results. In this short article, we scrutinize one of the serious problems we identified, report other concerns, and point out a potential bias in analyzing iconic shark species in general.
Biology and Life Sciences, Animal Science, Veterinary Science and Zoology
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Commenter: Shigehiro Kuraku
The commenter has declared there is no conflict of interests.