Preprint Article Version 1 This version is not peer-reviewed

Colorimetric Technique for Antimony Detection Based on the Use of Gold Nanoparticles Conjugated with Poly-A Oligonucleotide

Version 1 : Received: 31 October 2019 / Approved: 1 November 2019 / Online: 1 November 2019 (04:17:42 CET)

How to cite: Berlina, A.N.; Komova, N.S.; Zherdev, A.V.; Gaur, M.S.; Dzantiev, B.B. Colorimetric Technique for Antimony Detection Based on the Use of Gold Nanoparticles Conjugated with Poly-A Oligonucleotide. Preprints 2019, 2019110002 (doi: 10.20944/preprints201911.0002.v1). Berlina, A.N.; Komova, N.S.; Zherdev, A.V.; Gaur, M.S.; Dzantiev, B.B. Colorimetric Technique for Antimony Detection Based on the Use of Gold Nanoparticles Conjugated with Poly-A Oligonucleotide. Preprints 2019, 2019110002 (doi: 10.20944/preprints201911.0002.v1).

Abstract

A simple and rapid positive–negative colorimetric approach to determine the presence of antimony ions based on the use of gold nanoparticles conjugated with oligonucleotide (poly-A sequence) is developed. Colorimetric measurements reveal that the aggregates of modified gold nanoparticles were afforded after adding antimony ions, thus changing the solution color from pink to blue. The results of aptamer’s interaction on the gold nanoparticle surface with target analyte can be detected either by photometry or by the naked eye. The realized assay provides rapid (2 min), sensitive (detection limit 10 ng/mL), specific, and precise (variation coefficient less than 3.8%) detection of antimony (III) in drinking water

Subject Areas

heavy metal analyses; gold nanoparticles; oligonucleotide; antimony; color change

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