Preprint Review Version 1 Preserved in Portico This version is not peer-reviewed

Hypothalamic Endocrine Tumors: An Update

Version 1 : Received: 25 September 2019 / Approved: 28 September 2019 / Online: 28 September 2019 (00:24:48 CEST)

A peer-reviewed article of this Preprint also exists.

Asa, S.L.; Mete, O. Hypothalamic Endocrine Tumors: An Update. J. Clin. Med. 2019, 8, 1741. Asa, S.L.; Mete, O. Hypothalamic Endocrine Tumors: An Update. J. Clin. Med. 2019, 8, 1741.


The hypothalamus is the site of synthesis and secretion of a number of endocrine peptides that are involved in the regulation of hormonal activity of the pituitary and other endocrine targets. Tumors of the hypothalamus have been recognized to have both structural and functional effects including hormone hypersecretion. The classification of these tumors had advanced over the last few years and biomarkers are now available to classify these tumors and provide accurate structure-function correlations. This review provides an overview of tumors in this region that is critical to metabolic homeostasis with a focus on advances in the diagnosis of gangliocytomas, neurocytomas and pituicytomas that are unique to this region.


hypothalamus; endocrine; gangliocytoma; neurocytoma; pituicytoma; hormones


Medicine and Pharmacology, Pathology and Pathobiology

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