Preprint Review Version 1 This version is not peer-reviewed

Some Questions and Answers About the Role of Hox Temporal Collinearity in Vertebrate Axial Patterning

Version 1 : Received: 13 September 2019 / Approved: 17 September 2019 / Online: 17 September 2019 (12:55:22 CEST)

How to cite: Durston, A. Some Questions and Answers About the Role of Hox Temporal Collinearity in Vertebrate Axial Patterning. Preprints 2019, 2019090192 (doi: 10.20944/preprints201909.0192.v1). Durston, A. Some Questions and Answers About the Role of Hox Temporal Collinearity in Vertebrate Axial Patterning. Preprints 2019, 2019090192 (doi: 10.20944/preprints201909.0192.v1).

Abstract

The vertebrate anterior-posterior (A-P = craniocaudal) axis is evidently made by a timing mechanism. Evidence has accumulated that tentatively identifies the A-P timer as being or involving Hox temporal collinearity. Here, I focus on the two current competing models based on this premise. Common features and points of dissent are examined and a common model is distilled from what remains. This is an attempt to make sense of the literature.

Subject Areas

Hox; collinearity; time space translation; gastrulation; Xenopus; BMP

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