Submitted:
13 September 2019
Posted:
17 September 2019
You are already at the latest version
Abstract
The vertebrate anterior-posterior (A-P = craniocaudal) axis is evidently made by a timing mechanism. Evidence has accumulated that tentatively identifies the A-P timer as being or involving Hox temporal collinearity. Here, I focus on the two current competing models based on this premise. Common features and points of dissent are examined and a common model is distilled from what remains. This is an attempt to make sense of the literature.
Keywords:
Hox
; collinearity
; time space translation
; gastrulation
; Xenopus
; BMP
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