Preprint Article Version 2 This version is not peer-reviewed

Radiation Doses and Cancer Risk from CT Pulmonary Angiography Examinations

Version 1 : Received: 23 July 2019 / Approved: 24 July 2019 / Online: 24 July 2019 (10:42:37 CEST)
Version 2 : Received: 21 August 2019 / Approved: 23 August 2019 / Online: 23 August 2019 (10:53:52 CEST)

How to cite: Haspi Harun, H.; Abdul Karim, M.K.; Abbas, Z.; Muniandy, S.C.; Sabarudin, A.; Hoong, N.K. Radiation Doses and Cancer Risk from CT Pulmonary Angiography Examinations. Preprints 2019, 2019070269 (doi: 10.20944/preprints201907.0269.v2). Haspi Harun, H.; Abdul Karim, M.K.; Abbas, Z.; Muniandy, S.C.; Sabarudin, A.; Hoong, N.K. Radiation Doses and Cancer Risk from CT Pulmonary Angiography Examinations. Preprints 2019, 2019070269 (doi: 10.20944/preprints201907.0269.v2).

Abstract

The present study aims to investigate radiation doses from Computed Tomography Pulmonary Angiography (CTPA) examinations based on the patient’s size and to estimate the probability of cancer risk induced from the examination. Data from 100 patients who had undergone CTPA examinations, such as scanning acquisition parameters, patient demography, as well as radiation dose exposure, were collected and analysed. All subjects which aged above 18 y/o were scanned using a Philips Brilliance 128 multi-detector CT (MDCT) scanner. The mean dose value for Volume Computed Tomography Dose Index (CTDIvol), Dose-Length Product (DLP) and effective dose (E) were 11.06 ± 7.17 mGy, 400.38 ± 259.10 mGy.cm and 8.68 ± 5.47 mSv respectively. In addition, with respective of patient’s effective diameter, the mean SSDE value for Group 1, Group 2 and Group 3 were 9.93 ± 3.89, 13.70 ± 9.04 and 22.29 ± 7.35, respectively. Cancer risk per million procedure was calculated based on te recommendation by the International Commission on Radiological Protection Publication 103 report. The organ dose and cancer risk attained for breast, lung and liver were 17.05 ± 10.40 mGy (194 per one million procedure), 17.55 ± 10.86 mGy (192 per one million procedure) and 15.04 ± 9.75 mGy (53 per one million procedure), respectively. In conclusion, CTDIvol underestimated, and SSDE was more accurate in describing the radiation dose. Lung and breast with larger lung effective diameter received the highest dose exposure which increase the probability of the cancer risk. Therefore, it is important to apply optimised protocols in order to reduce patient’s exposure during CTPA examination.

Subject Areas

computed tomography; radiation dose; cancer risk; CTPA; lung effective diameter

Comments (1)

Comment 1
Received: 23 August 2019
Commenter: Muhammad Khalis Abdul Karim
Commenter's Conflict of Interests: Author
Comment: Update some information
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