Working Paper Article Version 3 This version is not peer-reviewed

Evaluating Radiation Dose and Effective Cancer Risk from CT Pulmonary Angiography Examinations: A Single Centre Study

Version 1 : Received: 23 July 2019 / Approved: 24 July 2019 / Online: 24 July 2019 (10:42:37 CEST)
Version 3 : Received: 6 August 2019 / Approved: 7 August 2019 / Online: 7 August 2019 (11:25:01 CEST)

How to cite: Haspi Harun, H.; Abdul Karim, M.K.; Abbas, Z.; Muniandy, S.C.; Sabarudin, A.; Hoong, N.K. Evaluating Radiation Dose and Effective Cancer Risk from CT Pulmonary Angiography Examinations: A Single Centre Study. Preprints 2019, 2019070269 Haspi Harun, H.; Abdul Karim, M.K.; Abbas, Z.; Muniandy, S.C.; Sabarudin, A.; Hoong, N.K. Evaluating Radiation Dose and Effective Cancer Risk from CT Pulmonary Angiography Examinations: A Single Centre Study. Preprints 2019, 2019070269

Abstract

Present study aims to investigate the usefulness and effect of SSDE and patient size in evaluating radiation dose in CTPA examination and to estimate its cancer risk. The records of 100 patients who had undergone CTPA were retrieved. The radiation dose exposure, scanning acquisition protocol, as well as patient characteristics, were noted. Radiation exposure presented as Volume Computed Tomography Dose Index (CTDIvol), Size-Specific Dose Estimate (SSDE), Dose-Length Product (DLP), and effective dose (E) and organ dose. Effective cancer risk per million procedure was calculated by referring to the International Commission on Radiological Protection Publication 103. The CTDIvol, SSDE, DLP and E were comparable within different lung effective diameter groups. The organ dose and effective cancer risk attained for breast, lung and liver were 17.05 ± 10.40 mGy (194 per one million procedure), 17.55 ± 10.86 mGy (192 per one million procedure) and 15.04 ± 9.75 mGy (53 per one million procedure), respectively. In conclusion, CTDIvol underestimated, and SSDE was more accurate in describing the radiation dose. The lung and breast of subjects with larger lung effective diameter were a higher risk of developing cancer as they received the highest exposure. Therefore, extra safety measures should be considered for optimising the patient’s exposure undergoing CTPA.

Subject Areas

Computed Tomography; radiation dose; cancer risk; CTPA; lung effective diameter

Comments (1)

Comment 1
Received: 7 August 2019
Commenter: Muhammad Khalis Abdul Karim
Commenter's Conflict of Interests: Author
Comment: Update new information
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