Version 1
: Received: 23 July 2019 / Approved: 24 July 2019 / Online: 24 July 2019 (10:42:37 CEST)
Version 2
: Received: 21 August 2019 / Approved: 23 August 2019 / Online: 23 August 2019 (10:53:52 CEST)
Version 3
: Received: 1 January 2020 / Approved: 3 January 2020 / Online: 3 January 2020 (11:21:25 CET)
How to cite:
Haspi Harun, H.; Abdul Karim, M.K.; Abbas, Z.; Muniandy, S.C.; Sabarudin, A.; Hoong, N.K. Association of Radiation Doses and Cancer Risks from CT Pulmonary Angiography Examinations in Relation to Body Effective Diameter. Preprints2019, 2019070269. https://doi.org/10.20944/preprints201907.0269.v3
Haspi Harun, H.; Abdul Karim, M.K.; Abbas, Z.; Muniandy, S.C.; Sabarudin, A.; Hoong, N.K. Association of Radiation Doses and Cancer Risks from CT Pulmonary Angiography Examinations in Relation to Body Effective Diameter. Preprints 2019, 2019070269. https://doi.org/10.20944/preprints201907.0269.v3
Haspi Harun, H.; Abdul Karim, M.K.; Abbas, Z.; Muniandy, S.C.; Sabarudin, A.; Hoong, N.K. Association of Radiation Doses and Cancer Risks from CT Pulmonary Angiography Examinations in Relation to Body Effective Diameter. Preprints2019, 2019070269. https://doi.org/10.20944/preprints201907.0269.v3
APA Style
Haspi Harun, H., Abdul Karim, M.K., Abbas, Z., Muniandy, S.C., Sabarudin, A., & Hoong, N.K. (2020). Association of Radiation Doses and Cancer Risks from CT Pulmonary Angiography Examinations in Relation to Body Effective Diameter. Preprints. https://doi.org/10.20944/preprints201907.0269.v3
Chicago/Turabian Style
Haspi Harun, H., Akmal Sabarudin and Ng Kwan Hoong. 2020 "Association of Radiation Doses and Cancer Risks from CT Pulmonary Angiography Examinations in Relation to Body Effective Diameter" Preprints. https://doi.org/10.20944/preprints201907.0269.v3
Abstract
This study aims to evaluate the patient’s dose exposure from Computed Tomography Pulmonary Angiography (CTPA) examination and to estimates the cancer risk induced from the examinations based on the patient’s size. One hundred patients were recruited, and data information was collected retrospectively. A multi-detector (MDCT) (Philips Brilliance 128, USA) scanner were utilized for the CTPA examination, and dose data were obtained from the system. The effective diameter of each subjects’ image was measured for the Size-specific dose estimates (SSDEs). All subjects divided into Group 1 (19 – 25 cm), Group 2 (25-28 cm) and Group 3 (28-38 cm), where the association between gender were analysed. Effective dose (E), SSDE, organ dose and cancer risk of each group were evaluated and compared statistically using independent t-test and one-way ANOVA. The range of mean CTDIvol, DLP and E values were (6.44 – 17.42 mGy), (239 – 631 mGy), (5.19 – 13.90 mSv), respectively. In respective with the patient’s effective diameter, the mean SSDE value for Group 1, Group 2 and Group 3 were 9.93 ± 3.89 mGy, 13.70 ± 9.04 mGy and 22.29 ± 7.35 mGy. The organ dose and cancer risk attained for breast, lung and liver were 17.05 ± 10.40 mGy (194 per one million procedure), 17.55 ± 10.86 mGy (192 per one million procedure) and 15.04 ± 9.75 mGy (53 per one million procedure), respectively. Lung and breast with more massive patient’s effective diameter received the highest dose exposure which increases the probability of the cancer risk. CTDIvol was found to be underestimated, and SSDE provides more accurate in describing the radiation dose and cancer risk. Body effective diameter found to be significant on the estimation except for gender. Therefore, it is essential to apply optimised protocols in order to reduce patient’s exposure during CTPA examination.
Keywords
Computed Tomography; radiation dose; cancer risk; CTPA; effective diameter
Subject
Physical Sciences, Radiation and Radiography
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Commenter: Muhammad Khalis Abdul Karim
Commenter's Conflict of Interests: Author