Preprint Article Version 1 Preserved in Portico This version is not peer-reviewed

Alzheimer's in Post-Industrial Epoch

Version 1 : Received: 28 May 2019 / Approved: 29 May 2019 / Online: 29 May 2019 (08:39:53 CEST)

How to cite: Kholmanskiy, A. Alzheimer's in Post-Industrial Epoch. Preprints 2019, 2019050345. Kholmanskiy, A. Alzheimer's in Post-Industrial Epoch. Preprints 2019, 2019050345.


Study nature of epidemiological risk factors and patterns of distribution of mortality from Alzheimer's (DA) in 160 countries. An exponential Malthus model was used to construct adequate approximations of statistical data. Proportionality of average lifetime after 55 years (Δt) to education index (Ψ) was established. Ranking of countries by increasing value of ΨΔt showed that DA depends exponentially on ΨΔt and all countries can be divided into three groups in accordance with level of their economic development. In series of countries of low, medium and highly developed, their average values of DA increase exponentially. Growth of DA in developed countries in post-industrial epoch was explained by emergence of a new risk factor Alzheimer's of a mental nature. A mismatch of complexity or, on contrary, primitiveness of profession with level of mental development of worker, provokes development of chronic stress in him, fraught with pathologies of cognitive function metabolism in elderly. The geography of Alzheimer's disease was explained by the dependence of the human mentality on latitudinal climate change and on the chiral factor of a solar nature acting at night on a sleeping person.


mortality; Alzheimer's; education; life expectancy; mentality; level of development


Medicine and Pharmacology, Psychiatry and Mental Health

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