Preprint Article Version 1 This version is not peer-reviewed

Flavonoid Glycosides from Endemic Bulgarian Astragalus aitosensis (Ivanisch.)

Version 1 : Received: 28 March 2019 / Approved: 29 March 2019 / Online: 29 March 2019 (09:13:02 CET)

A peer-reviewed article of this Preprint also exists.

Vasilev, H.; Ross, S.; Šmejkal, K.; Maršík, P.; Jankovská, D.; Havlík, J.; Veselý, O. Flavonoid Glycosides from Endemic Bulgarian Astragalus aitosensis (Ivanisch.). Molecules 2019, 24, 1419. Vasilev, H.; Ross, S.; Šmejkal, K.; Maršík, P.; Jankovská, D.; Havlík, J.; Veselý, O. Flavonoid Glycosides from Endemic Bulgarian Astragalus aitosensis (Ivanisch.). Molecules 2019, 24, 1419.

Journal reference: Molecules 2019, 24, 1419
DOI: 10.3390/molecules24071419

Abstract

Astragalus is a very interesting plant genus well-known for content of flavonoids, triterpenes and polysaccharides. Its secondary metabolites are described as biologically active compounds showing a number of activities, like immunomodulating, antibacterial, antiviral and hepatoprotective. This inspired us to analyze the Bulgarian endemic A. aitosensis (Ivanisch.) to obtain deeper information about its phenolic components. We used extensive chromatographic separation of A. aitosensis extract to obtain seven phenolic compounds (17), which were identified using combined LC-MS and NMR spectral studies. The 1D and 2D NMR analysis and HR-MS allowed us to resolve the structures of known compounds 57 as isorhamnetin-3-O-robinobioside, isorhamnetin-3-O-(2,6-di-O-α-rhamno-pyranosyl-β-galactopyranoside), and alangiflavoside, respectively, and further comparison of these spectral data with available literature helped us with structural analysis of newly described flavonoid glycosides 14. These were described in plant source for the first time.

Subject Areas

Astragalus aitosensis; flavonoid; glycoside

Comments (0)

We encourage comments and feedback from a broad range of readers. See criteria for comments and our diversity statement.

Leave a public comment
Send a private comment to the author(s)
Views 0
Downloads 0
Comments 0
Metrics 0


×
Alerts
Notify me about updates to this article or when a peer-reviewed version is published.