Preprint Article Version 1 Preserved in Portico This version is not peer-reviewed

Conjunctivitis and Exposure to Ambient Ozone

Version 1 : Received: 11 January 2019 / Approved: 14 January 2019 / Online: 14 January 2019 (09:49:56 CET)
Version 2 : Received: 16 April 2019 / Approved: 17 April 2019 / Online: 17 April 2019 (11:58:14 CEST)

How to cite: Szyszkowicz, M.; Gordon Shaag, A.; Shneor, E. Conjunctivitis and Exposure to Ambient Ozone. Preprints 2019, 2019010128. Szyszkowicz, M.; Gordon Shaag, A.; Shneor, E. Conjunctivitis and Exposure to Ambient Ozone. Preprints 2019, 2019010128.


The purpose of this study is to assess the concentration-response relations between conjunctivitis and exposure to ambient ozone. This retrospective study includes emergency department (ED) visits for conjunctivitis in Edmonton, Canada, for the period April 1992 – March 2002. Daily average levels of ozone, of temperature and relative humidity were estimated and used for the period of the study. For each of the considered exposure lags, from 0 to 9 days, six various models were fitted to estimate the concentration-response function. The goodness of fit was assessed using Akaike information criterion. During the period of the study, 17,211 ED visits for conjunctivitis were recorded and used. For all subjects together, a positive statistically significant association was obtained for the exposure lagged by 5 days. For female subjects, lags 1, 3, and 9 had positive statistically significant associations (lag 2 had negative associations). For male subjects only lag 5 had a positive statistically significant association. The estimated non-linear concentration-response functions for the considered groups (all, males, females) and lags, revealed the associations along the exposure levels. The fitted shapes are described by the parameters and may have various forms. The estimated function are useful to determine the risk associated with exposure to ground-level ozone.


air pollution; conjunctivitis; exposure; linear; model; case-crossover; poisson


Medicine and Pharmacology, Ophthalmology

Comments (0)

We encourage comments and feedback from a broad range of readers. See criteria for comments and our Diversity statement.

Leave a public comment
Send a private comment to the author(s)
* All users must log in before leaving a comment
Views 0
Downloads 0
Comments 0
Metrics 0

Notify me about updates to this article or when a peer-reviewed version is published.
We use cookies on our website to ensure you get the best experience.
Read more about our cookies here.