Preprint Review Version 1 This version is not peer-reviewed

Optical Biosensors Based on Silicon-On-Insulator Ring Resonator: A Review

Version 1 : Received: 31 December 2018 / Approved: 3 January 2019 / Online: 3 January 2019 (11:41:49 CET)

A peer-reviewed article of this Preprint also exists.

Steglich, P.; Hülsemann, M.; Dietzel, B.; Mai, A. Optical Biosensors Based on Silicon-On-Insulator Ring Resonators: A Review. Molecules 2019, 24, 519. Steglich, P.; Hülsemann, M.; Dietzel, B.; Mai, A. Optical Biosensors Based on Silicon-On-Insulator Ring Resonators: A Review. Molecules 2019, 24, 519.

Journal reference: Molecules 2019, 24, 519
DOI: 10.3390/molecules24030519

Abstract

Recent developments in optical biosensors based on integrated photonic devices are reviewed with a special emphasis on silicon-on-insulator ring resonator. The review is mainly devoted to the following aspects: (1) Principles of sensing mechanism, (2) sensor design, (3) biofunctionalization procedures for specific molecule detection and (4) measurement set-ups and advances in chip-integration. The inherent challenges of implementing photonics-based biosensors to meet specific requirements of applications in medicine, food analysis, and environmental monitoring are discussed.

Subject Areas

biosensors; biophotonics; integrated optical sensors; aptamers; biomaterials; optical sensor; silicon photonics; ring resonators; lab-on-a-chip

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