Preprint Article Version 1 Preserved in Portico This version is not peer-reviewed

Fluid-Structure Interaction in Abdominal Aortic Aneurysms: Effect of Haematocrit

Version 1 : Received: 14 December 2018 / Approved: 17 December 2018 / Online: 17 December 2018 (15:50:54 CET)

A peer-reviewed article of this Preprint also exists.

Stergiou, Y.G.; Kanaris, A.G.; Mouza, A.A.; Paras, S.V. Fluid-Structure Interaction in Abdominal Aortic Aneurysms: Effect of Haematocrit. Fluids 2019, 4, 11. Stergiou, Y.G.; Kanaris, A.G.; Mouza, A.A.; Paras, S.V. Fluid-Structure Interaction in Abdominal Aortic Aneurysms: Effect of Haematocrit. Fluids 2019, 4, 11.

Abstract

The Abdominal Aortic Aneurysm (AAA) is a local dilation of the abdominal aorta and it is a cause for serious concern because of the high mortality associated with its rupture. Consequently, the understanding of the phenomena related to the creation and the progression of an AAA is of crucial importance. In this work the complicated interaction between the blood flow and the AAA wall is numerically examined using a fully coupled Fluid-Structure Interaction (FSI) method. The study investigates the possible link between the dynamic behaviour of an AAA and the blood viscosity variations attributed to the haematocrit value, while it also incorporates the pulsatile blood flow, the non-Newtonian behaviour of blood and the hyperelasticity of the arterial wall. It was found that blood viscosity has no significant effect on von Mises stress magnitude and distribution, whereas there is a close relation between the haematocrit value and the Wall Shear Stress (WSS) magnitude in AAAs. This WSS variation can possibly alter the mechanical properties of the arterial wall and increase its growth rate or even its rupture possibility. The relationship between haematocrit and dynamic behaviour of an AAA can be helpful in designing a patient specific treatment.

Keywords

Abdominal Aortic Aneurysm; FSI; CFD; haematocrit; pulsatile flow; non-Newtonian

Subject

Medicine and Pharmacology, Oncology and Oncogenics

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