ZIF Nanocrystal-Based SAW Electronic Nose to Detect Diabetes in Human Breath

Fabio A. Bahos; Arianee Sainz-Vidal; Celia Sánchez-Pérez; José M. Saniger; Isabel Gràcia; María M. Saniger-Alba; Daniel Matatagui

doi:10.20944/preprints201811.0210.v1

Preprint Article Version 1 Preserved in Portico This version is not peer-reviewed

Version 1 : Received: 7 November 2018 / Approved: 8 November 2018 / Online: 8 November 2018 (11:18:23 CET)

In the present work a novel, portable and innovative eNose composed of a surface acoustic wave (SAW) sensor array based ZIF-8, and ZIF-67 nanocrystals (pure and combined with gold nanoparticles) as sensitive layers has been tested as a non-invasive system to detect and differentiate disease markers, such as acetone, ethanol and ammonia, related with early diagnosis of diabetes mellitus through exhaled breath. The sensors have been prepared by spin coating, achieving continuous and homogenous sensitive layers. Low concentrations (5 ppm, 10 ppm and 25ppm) of the marker analytes were measured, obtaining high sensitivities, good reproducibility, short time response and fast signal recovery.

eNose; gas sensor, SAW; Surface Acoustic Wave, Love wave, diabetes, breath, VOC, ZIF, Zeolite

Medicine and Pharmacology, Other

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ZIF Nanocrystal-Based SAW Electronic Nose to Detect Diabetes in Human Breath

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