Freeform Perfusable Microfluidics Embedded in Hydrogel Matrices

Gabriela Štumberger; Boštjan Vihar

doi:10.20944/preprints201811.0072.v1

Preprint Communication Version 1 Preserved in Portico This version is not peer-reviewed

Version 1 : Received: 2 November 2018 / Approved: 2 November 2018 / Online: 2 November 2018 (16:54:05 CET)

We report a modification of the freeform reversible embedding of suspended hydrogels (FRESH) 3D printing method for the fabrication of freeform perfusable microfluidics inside a hydrogel matrix. Xanthan gum is deposited into a CaCl2 infused gelatin slurry to form filaments, which are consequently rinsed to produce hollow channels. This provides a simple method for rapid prototyping of microfluidic devices based on biopolymers and potentially a new approach to the construction of vascular grafts for tissue engineering.

Freeform, hydrogel, gelatin, microfluidics, FRESH, bioprinting, vascularization

Biology and Life Sciences, Biology and Biotechnology

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Freeform Perfusable Microfluidics Embedded in Hydrogel Matrices

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