Preprint Review Version 1 This version is not peer-reviewed

Noninvasive Electromagnetic Wave Sensing of Glucose

Version 1 : Received: 1 October 2018 / Approved: 1 October 2018 / Online: 1 October 2018 (14:04:05 CEST)

How to cite: Zhang, R.; Liu, S.; Jin, H.; Luo, Y.; Zheng, Z.; Gao, F.; Zheng, Y. Noninvasive Electromagnetic Wave Sensing of Glucose. Preprints 2018, 2018100012 (doi: 10.20944/preprints201810.0012.v1). Zhang, R.; Liu, S.; Jin, H.; Luo, Y.; Zheng, Z.; Gao, F.; Zheng, Y. Noninvasive Electromagnetic Wave Sensing of Glucose. Preprints 2018, 2018100012 (doi: 10.20944/preprints201810.0012.v1).

Abstract

Diabetic patients need long-term and frequent glucose monitoring to assist in insulin intake. The current finger-prick devices are painful and costly which make noninvasive glucose sensors highly demanded. In this review paper, we discuss several advanced electromagnetic (EM) wave based technologies for noninvasive glucose measurement, including infrared (IR) spectroscopy, photoacoustic (PA) spectroscopy, Raman spectroscopy, fluorescence, optical coherent tomography (OCT) and microwave sensing. Development and progress of each method are discussed regarding fundamental principle, system setup and experimental results. Despite the promising achievements reported previously, there is no established product to obtain FDA approval or survive marketing test. Limitations and prospects of these techniques are discussed at the end of this review.

Subject Areas

noninvasive glucose measurement; IR spectroscopy; Raman spectroscopy; photoacoustic spectroscopy; microwave sensing

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