Preprint Article Version 1 This version is not peer-reviewed

Enamel Anti-Demineralization Effect of Orthodontic Adhesive Containing Bioactive Glass and Graphene Oxide: an in-Vitro Study

Version 1 : Received: 21 August 2018 / Approved: 21 August 2018 / Online: 21 August 2018 (16:24:58 CEST)

A peer-reviewed article of this Preprint also exists.

Lee, S.-M.; Yoo, K.-H.; Yoon, S.-Y.; Kim, I.-R.; Park, B.-S.; Son, W.-S.; Ko, C.-C.; Son, S.-A.; Kim, Y.-I. Enamel Anti-Demineralization Effect of Orthodontic Adhesive Containing Bioactive Glass and Graphene Oxide: An In-Vitro Study. Materials 2018, 11, 1728. Lee, S.-M.; Yoo, K.-H.; Yoon, S.-Y.; Kim, I.-R.; Park, B.-S.; Son, W.-S.; Ko, C.-C.; Son, S.-A.; Kim, Y.-I. Enamel Anti-Demineralization Effect of Orthodontic Adhesive Containing Bioactive Glass and Graphene Oxide: An In-Vitro Study. Materials 2018, 11, 1728.

Journal reference: Materials 2018, 11, 1728
DOI: 10.3390/ma11091728

Abstract

White spot lesions (WSLs), a side effect of orthodontic treatment, can result in reversible and unaesthetic results. Graphene oxide (GO) with a bioactive glass (BAG) mixture([email protected]) was added to Low Viscosity Transbond XT(LV) in a ratio of 1, 3, 5%. The composite’s characterization and its physical and biological properties were verified with scanning electron microscopy(SEM) and X-ray diffraction(XRD); its microhardness, shear bond stress (SBS), cell viability, and adhesive remnant index (ARI) were also assessed. Efficiency in reducing WSL was evaluated using antibacterial activity of S. mutans. Anti-demineralization was analyzed using a cycle of the acid-base solution. Adhesives with 3 or 5 wt.% of [email protected] showed significant increase in microhardness compared with LV. The sample and LV groups showed no significant differences in SBS or ARI. The cell viability test confirmed that none of the sample groups showed higher toxicity compared to the LV group. Antibacterial activity was higher in the 48-hour group than in the 24-hour group; the 48-hour test showed that [email protected] had a high antibacterial effect, which was more pronounced in 5 wt.% of [email protected] Anti-demineralization effect was higher in the [email protected] than in the LV-group; the higher the [email protected] concentration, the higher the anti-demineralization effect.

Subject Areas

anti-demineralization ; antibacterial effect; white spot lesion; graphene oxide; bioactive glass

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