Preprint Article Version 1 This version is not peer-reviewed

The Effects of a Pine Bark Extract on Exercise Performance and Post Exercise Inflammation, Oxidative Stress, Muscle Soreness and Damage

Version 1 : Received: 16 August 2018 / Approved: 17 August 2018 / Online: 17 August 2018 (12:07:49 CEST)

How to cite: Aldret, R.; Bellar, D. The Effects of a Pine Bark Extract on Exercise Performance and Post Exercise Inflammation, Oxidative Stress, Muscle Soreness and Damage. Preprints 2018, 2018080303 (doi: 10.20944/preprints201808.0303.v1). Aldret, R.; Bellar, D. The Effects of a Pine Bark Extract on Exercise Performance and Post Exercise Inflammation, Oxidative Stress, Muscle Soreness and Damage. Preprints 2018, 2018080303 (doi: 10.20944/preprints201808.0303.v1).

Abstract

The purpose of the present study was to examine if 14 days of supplementation with a pine bark extract leading up to and following an exercise test would increase performance and reduce biomarkers associated with muscle damage, inflammation and oxidative stress. The study used a double-blind, placebo controlled, cross-over design. Participants ingested either 800mg pine bark extract or placebo for 14 days prior to the first exercise trial and for 2 days post-exercise. On the exercise day, participants submitted a pre-exercise blood sample, then completed a VO2 peak test until volitional failure. A post-blood sample was collected 1 hour after completion of exercise. Participants returned at 24 & 48 hours after the exercise testing for measures of muscle pain in the lower body using an algometer. Participants then had a 7-day washout period before beginning to crossing over to the alternate treatment. Analysis via ordinal regression demonstrated a significant difference in oxidative stress in the pine bark extract group compared to placebo (ChiSq = 2.63; p = 0.05). The pine bark extract was effective at affording protection from oxidative stress post exercise. Further work should be undertaken to evaluate the findings with other exercise modes or in participants with known metabolic syndrome. 

Subject Areas

pine bark extract; oxidative stress; muscle damage

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