Preprint Article Version 1 Preserved in Portico This version is not peer-reviewed

In Silico Phylogenetic and Structural Analysis of Plant Damps

Version 1 : Received: 26 July 2018 / Approved: 26 July 2018 / Online: 26 July 2018 (16:08:54 CEST)

How to cite: pavlopoulou, A.; Karaca, E.; Balestrazzi, A.; Georgakilas, A. In Silico Phylogenetic and Structural Analysis of Plant Damps. Preprints 2018, 2018070522. https://doi.org/10.20944/preprints201807.0522.v1 pavlopoulou, A.; Karaca, E.; Balestrazzi, A.; Georgakilas, A. In Silico Phylogenetic and Structural Analysis of Plant Damps. Preprints 2018, 2018070522. https://doi.org/10.20944/preprints201807.0522.v1

Abstract

In plants and animals, endogenous biological molecules, termed damage-associated molecular patterns (DAMPs) or alarmins, are released by damaged, stressed or dying cells following abiotic stress such as radiation and drought stress. In turn, a cascade of downstream signaling events is initiated leading to the up-regulation of defense-related genes. In the present study, in an effort to investigate the conservation status of the molecular mechanisms implicated in the danger signaling, thorough in silico phylogenetic and structural analyses of the effector biomolecules were performed in taxonomically diverse plant species. On the basis of our results, the defense mechanisms appear to be largely conserved within the plant kingdom. Of note is our finding that the sequence and/or function of several components of these mechanisms were found to be conserved in animals, as well.

Keywords

DAMPs; alarmins; innate immune response; plants; phylogeny; in silico

Subject

Biology and Life Sciences, Plant Sciences

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