Pero, R.; Fico, G.; Scudiero, O.; Laneri, S. Microbiota and LPS-Induced Obesity Inflammation: Therapeutic Implications. Preprints2018, 2018070375. https://doi.org/10.20944/preprints201807.0375.v1
APA Style
Pero, R., Fico, G., Scudiero, O., & Laneri, S. (2018). Microbiota and LPS-Induced Obesity Inflammation: Therapeutic Implications<strong> </strong>. Preprints. https://doi.org/10.20944/preprints201807.0375.v1
Chicago/Turabian Style
Pero, R., Olga Scudiero and Sonia Laneri. 2018 "Microbiota and LPS-Induced Obesity Inflammation: Therapeutic Implications<strong> </strong>" Preprints. https://doi.org/10.20944/preprints201807.0375.v1
Abstract
Obesity and chronic low-grade inflammation are becoming global epidemics. The dysbiosis has a specific role in the metabolism and energy stocks of the host. The discovery that a low-grade of inflammation could be directly connected to the intestinal microbiota metabolic endotoxemia (elevated levels of plasma lipopolysaccharides) has allowed the identification of novel mechanisms involved in the control of the intestinal barrier. In this review, it will analyze the latest news to explain how human symbiotic microorganisms participate in the growth of the fat reserves and promote insulin resistance as a low-grade inflammation. Besides, it will discuss new treatments with probiotics and prebiotics as a promising therapeutic approach to reverse the host's metabolic changes linked to dysbiosis observed in obesity.
Medicine and Pharmacology, Dietetics and Nutrition
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
