preprints.org > medicine and pharmacology > neuroscience and neurology > doi: 10.20944/preprints201803.0018.v2

Preprint Article Version 2 Preserved in Portico This version is not peer-reviewed

Version 1 : Received: 1 March 2018 / Approved: 2 March 2018 / Online: 2 March 2018 (05:16:16 CET)
Version 2 : Received: 16 April 2018 / Approved: 17 April 2018 / Online: 17 April 2018 (08:35:18 CEST)

Objective: to evaluate the effects of excitatory repetitive transcranial magnetic stimulation (rTMS) of the international 10-20 system P3 point (intraparietal sulcus region) in chronic patients with a frontal lesion and parietal sparing due to stroke on the impaired upper (UL) and lower limb (LL) as measured by Fugl-Meyer Assessment (FMA). Methods: three patients (C1: 49.83/2.75, C2: 53.17/3.83, C3: 63.33/3.08 years-old at stroke/ years post-stroke, respectively) received two weeks (five days/ week) of rTMS at 10 Hz of P3. A patient was treated in similar conditions with a sham coil (S1: 56.58/4.33). No complimentary therapy was delivered during the study. Patients were evaluated before, after- and two months post-treatment (A1, A2 and A3, respectively). Results: we found increased scores for LL in motor function subsection for C1 and C3 and in sensory function for C2 by A2 that remained at A3. We also found an increased score for UL motor function for C2 and C3, but the score decreased by A3 for C2. C3 score for UL range of motion increased by A3 compared to A1 and A2. Conclusion: In a variable way, P3 excitatory rTMS increased FMA scores in different upper and lower limb subsections of our three treated patients.

intraparietal sulcus; stroke; rTMS; Fugl-Meyer Assessment; fast frequency TMS; motricity; sensibility; chronic patients

Medicine and Pharmacology, Neuroscience and Neurology

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