Preprint Article Version 1 This version is not peer-reviewed

Broadband Terahertz Light-Matter Interaction Enhancement for Precise Spectroscopy of Thin Films and Micro-Samples

Version 1 : Received: 25 February 2018 / Approved: 26 February 2018 / Online: 26 February 2018 (09:30:06 CET)

A peer-reviewed article of this Preprint also exists.

Peretti, R.; Braud, F.; Peytavit, E.; Dubois, E.; Lampin, J.-F. Broadband Terahertz Light–Matter Interaction Enhancement for Precise Spectroscopy of Thin Films and Micro-Samples. Photonics 2018, 5, 11. Peretti, R.; Braud, F.; Peytavit, E.; Dubois, E.; Lampin, J.-F. Broadband Terahertz Light–Matter Interaction Enhancement for Precise Spectroscopy of Thin Films and Micro-Samples. Photonics 2018, 5, 11.

Journal reference: Photonics 2018, 5, 11
DOI: 10.3390/photonics5020011

Abstract

In biology molecules and macromolecules like sugars, proteins, DNA, and RNA are of utter importance. Detecting their presence as well as their conformation is still a challenge in many cases. It is well known that the vibrational states of such molecules lie from the infrared to the TeraHertz range. Spectroscopy can be used to detect such compounds and probe their conformation. Still, terahertz spectroscopy on biosample is a challenge for two main reasons: water absorption; and the small size of the samples. The sample volume is smaller than the cube of the TeraHertz wavelength; the light matter interactions are thus extremely reduced. In this paper, we present the design, fabrication, characterization and the first typical uses of a biophotonic device aiming at increasing light matter interaction to enable terahertz spectroscopy of minute samples on a broad band (0.2–2 THz). We demonstrate time domain spectroscopy experiments on few µl samples showing the validity of our approach.

Subject Areas

biophotonic; Terahertz; time domain spectroscopy; absorption enhancement; laser cutting

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