Peretti, R.; Braud, F.; Peytavit, E.; Dubois, E.; Lampin, J.-F. Broadband Terahertz Light–Matter Interaction Enhancement for Precise Spectroscopy of Thin Films and Micro-Samples. Photonics2018, 5, 11.
Peretti, R.; Braud, F.; Peytavit, E.; Dubois, E.; Lampin, J.-F. Broadband Terahertz Light–Matter Interaction Enhancement for Precise Spectroscopy of Thin Films and Micro-Samples. Photonics 2018, 5, 11.
Peretti, R.; Braud, F.; Peytavit, E.; Dubois, E.; Lampin, J.-F. Broadband Terahertz Light–Matter Interaction Enhancement for Precise Spectroscopy of Thin Films and Micro-Samples. Photonics2018, 5, 11.
Peretti, R.; Braud, F.; Peytavit, E.; Dubois, E.; Lampin, J.-F. Broadband Terahertz Light–Matter Interaction Enhancement for Precise Spectroscopy of Thin Films and Micro-Samples. Photonics 2018, 5, 11.
Abstract
In biology molecules and macromolecules like sugars, proteins, DNA, and RNA are of utter importance. Detecting their presence as well as their conformation is still a challenge in many cases. It is well known that the vibrational states of such molecules lie from the infrared to the TeraHertz range. Spectroscopy can be used to detect such compounds and probe their conformation. Still, terahertz spectroscopy on biosample is a challenge for two main reasons: water absorption; and the small size of the samples. The sample volume is smaller than the cube of the TeraHertz wavelength; the light matter interactions are thus extremely reduced. In this paper, we present the design, fabrication, characterization and the first typical uses of a biophotonic device aiming at increasing light matter interaction to enable terahertz spectroscopy of minute samples on a broad band (0.2–2 THz). We demonstrate time domain spectroscopy experiments on few µl samples showing the validity of our approach.
Keywords
biophotonic; Terahertz; time domain spectroscopy; absorption enhancement; laser cutting
Subject
Physical Sciences, Optics and Photonics
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
