Review
Version 1
Preserved in Portico This version is not peer-reviewed
Meningococcal Vaccines: Current Status and Emerging Strategies
Version 1
: Received: 30 January 2018 / Approved: 31 January 2018 / Online: 31 January 2018 (03:07:42 CET)
A peer-reviewed article of this Preprint also exists.
McCarthy, P.C.; Sharyan, A.; Sheikhi Moghaddam, L. Meningococcal Vaccines: Current Status and Emerging Strategies. Vaccines 2018, 6, 12. McCarthy, P.C.; Sharyan, A.; Sheikhi Moghaddam, L. Meningococcal Vaccines: Current Status and Emerging Strategies. Vaccines 2018, 6, 12.
Abstract
Neisseria meningitidis causes most cases of bacterial meningitis. Meningococcal meningitis is a public health burden to both developed and developing countries throughout the world. There are a number of vaccines (polysaccharide-based, glycoconjugate, protein-based and combined conjugate vaccines) that are approved to target five of the six disease-causing serogroups of the pathogen. Immunization strategies have been effective at helping to decrease the global incidence of meningococcal meningitis. Researchers continue to enhance these efforts through discovery of new antigen targets that may lead to a broadly protective vaccine and development of new methods of homogenous vaccine production. This review describes current meningococcal vaccines and discusses some recent research discoveries that may transform vaccine development against N. meningitidis in the future.
Keywords
Neisseria meningitidis; glycoconjugate vaccines; protein-based vaccines, vaccine development
Subject
Biology and Life Sciences, Immunology and Microbiology
Copyright: This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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