Preprint Article Version 1 This version is not peer-reviewed

Development of Non-Enzymatic Glucose Biosensors Based on Electrochemically Prepared Polypyrrole-Chitosan-Titanium Dioxide Nanocomposite Films

Version 1 : Received: 3 April 2017 / Approved: 4 April 2017 / Online: 4 April 2017 (09:27:36 CEST)

A peer-reviewed article of this Preprint also exists.

AL-Mokaram, A.M.A.A.A.; Yahya, R.; Abdi, M.M.; Mahmud, H.N.M.E. The Development of Non-Enzymatic Glucose Biosensors Based on Electrochemically Prepared Polypyrrole–Chitosan–Titanium Dioxide Nanocomposite Films. Nanomaterials 2017, 7, 129. AL-Mokaram, A.M.A.A.A.; Yahya, R.; Abdi, M.M.; Mahmud, H.N.M.E. The Development of Non-Enzymatic Glucose Biosensors Based on Electrochemically Prepared Polypyrrole–Chitosan–Titanium Dioxide Nanocomposite Films. Nanomaterials 2017, 7, 129.

Journal reference: Nanomaterials 2017, 7, 129
DOI: 10.3390/nano7060129

Abstract

The performance of modified electrode of nanocomposite film consisting of polypyrrole-chitosan-titanium dioxide (Ppy-CS-TiO2) has been explored as non-enzymatic glucose biosensors. The synergy effect of TiO2 nanoparticles and conducting polymer on the current response of electrode resulted in higher sensitivity for nanocomposite modified electrode. The incorporation of TiO2 nanoparticles in the nanocomposite films were confirmed by XPS spectra. The FESEM and HR-TEM provided more evidences for the presence of TiO2 in Ppy-CS structure. Glucose biosensing properties were determined by amperommetry and cyclic voltammetry (CV) methods. The interfacial properties of nanocomposite electrodes were studied by electrochemical impedance spectroscopy (EIS). The developed biosensors showed a good sensitivity over the liner range of 1-14 mM with a detection limit of 614 μM for glucose. It also exhibited good selectivity and long term stability with no interference effect. The Ppy-CS-TiO2 nanocomposites film presented high electron transfer kinetics.

Subject Areas

nanomaterials; non-enzymatic glucose biosensors; nanocomposites; electrodeposition; titanium dioxide nanocomposite; XPS; EIS.

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