Contemporary approaches to comparative national assessment have produced a wide range of indicators measuring governance quality, human development, institutional effectiveness, innovation performance, and state fragility. Although these frameworks have significantly advanced comparative political analysis, they remain primarily oriented toward assessing current conditions, institutional outputs, or accumulated capacities. They provide limited insight into a fundamental question facing political communities in an era of systemic disruption: why do some nations successfully renew themselves while others remain trapped in cycles of decline, fragility, and institutional stagnation?This article introduces the Nationesis Index (NI), a novel composite framework designed to conceptualize and measure national regenerative capacity. Building on complexity theory, adaptive governance, institutional evolution, resilience studies, and theories of collective intelligence, Nationesis conceptualizes nations as complex adaptive political systems capable of learning, reorganizing, innovating, and transforming under conditions of uncertainty. The article develops the theoretical foundations of national regeneration and proposes eight interconnected dimensions of the Nationesis Index: institutional regeneration, cognitive capacity, innovation capacity, social cohesion, adaptive governance, ecological resilience, economic transformation, and symbolic legitimacy.Methodologically, the article presents a framework for index construction based on indicator selection, normalization procedures, multidimensional weighting, composite aggregation, sensitivity analysis, and expert-based validation. A preliminary illustrative application demonstrates the potential of the NI for comparative political analysis while acknowledging the need for further empirical testing. Unlike conventional indices that primarily evaluate how well nations perform at a given moment, the Nationesis Index addresses a different analytical challenge: how capable nations are of regenerating themselves through learning, adaptation, and systemic transformation.By introducing national regeneration as a distinct analytical construct, this article contributes to debates on political development, state capacity, resilience, and adaptive governance. It proposes a new research agenda for understanding nations not only as institutional arrangements but as evolving living systems.