Hepatic and splenic flexures are important anatomical landmarks in colonoscopy, supporting segmental orientation, lesion localisation, and bowel preparation assessment. This exploratory study investigated whether liver- and spleen-related shadow patterns visible on the colonic wall could serve as indirect cues for flexure localisation. We developed a preliminary workflow combining colour-based annotation and deep learning semantic segmentation. Representative shadow and mucosal regions were used to extract colour characteristics, while lumen/borders and artefacts were identified using luminance-based criteria. Based on these rules, 500 colonoscopy frames with visible shadows were automatically annotated and used to train a segmentation network for four classes: shadows, intestinal mucosa, lumen/borders, and artefacts. The trained model was then applied frame by frame to colonoscopy videos to generate temporal profiles of the segmented regions. In a representative test video, shadow clusters appeared near expert-indicated flexure regions after empirical filtering of frames not matching several criteria. These preliminary findings suggest that liver- and spleen-related shadows may provide complementary cues for flexure localisation in selected cases. However, the method remains exploratory and requires validation on larger, independently annotated datasets.