Submitted:
21 May 2026
Posted:
22 May 2026
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Abstract
Keywords:
1. Introduction
2. Materials and Methods
3. Results
4. Discussion
5. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Acknowledgments
Conflicts of Interest
Abbreviations
| AI | Artificial Intelligence |
| 3DGAN | Three-Dimensional Generative Adversarial Network |
| HD | Hausdorff Distance |
| STL | Standard Tessellation Language |
| RMS | Root Mean Square |
References
- Miyazaki, T.; Hotta, Y.; Kunii, J.; Kuriyama, S.; Tamaki, Y. A review of dental CAD/CAM: current status and future perspectives. J. Prosthodont Res. 2009, 53, 123–132. [Google Scholar]
- Rekow, E.D. Digital dentistry: the new state of the art—Is it disruptive or destructive? Dent. Mater. 2020, 36, 9–24. [Google Scholar] [CrossRef] [PubMed]
- Schwendicke, F.; Samek, W.; Krois, J. Artificial intelligence in dentistry: chances and challenges. J. Dent. Res. 2020, 99, 769–774. [Google Scholar] [CrossRef] [PubMed]
- Khanagar, S.B.; Al-Ehaideb, A.; Maganur, P.C.; et al. Developments, application, and performance of artificial intelligence in dentistry – A systematic review. J. Dent. Sci. 2021, 16, 508–522. [Google Scholar] [CrossRef] [PubMed]
- Goodfellow, I.; Pouget-Abadie, J.; Mirza, M.; et al. Generative adversarial nets. Adv. Neural Inf. Process Syst. 2014, 27, 2672–2680. [Google Scholar]
- Yi, X.; Walia, E.; Babyn, P. Generative adversarial network in medical imaging: A review. Med. Image Anal. 2019, 58, 101552. [Google Scholar] [CrossRef] [PubMed]
- Lerner, H.; Nagy, K.; Fehér, A.; et al. Artificial intelligence in dental CAD/CAM: a review. BMC Oral. Health 2022, 22, 1. [Google Scholar]
- Ding, Y.; Zhang, J.; Liu, X.; et al. Automated design of dental crowns using deep learning. Comput Biol. Med. 2021, 134, 104494. [Google Scholar]
- Mangano, F.; Admakin, O.; Bonacina, M.; et al. Artificial intelligence and dental implants: a systematic review. Int. J. Env. Res. Public Health 2021, 18, 9736. [Google Scholar]
- Kostadinov, G.; Naydenov, A. 3D Cycle-Consistent Adversarial Network for Designing Dental Implant Crown. Comput. Sci. Educ. Comput. Sci. CSECS 2024, 609. [Google Scholar]
- Ding, H.; Cui, Z.; Maghami, E.; Chen, Y.; Matinlinna, J.P.; Pow, E.H.N.; Fok, A.S.L.; Burrow, M.F.; Wang, W.; Tsoi, J.K.H. Morphology and mechanical performance of dental crown designed by 3D-DCGAN. Dent. Mater. 2023, 39, 320–332. [Google Scholar] [CrossRef] [PubMed]
- Liu, C.M.; Lin, W.C.; Lee, S.Y. Evaluation of the efficiency, trueness, and clinical application of novel artificial intelligence design for dental crown prostheses. Dent. Mater. 2024, 40, 19–27. [Google Scholar] [CrossRef] [PubMed]
- Kong, H.J.; Yang, S.; Lee, J.H.; et al. Application of artificial intelligence in dental crown prosthesis: a scoping review. BMC Oral. Health 2024, 24, 890. [Google Scholar] [CrossRef] [PubMed]
- Kong, H.J.; et al. Accuracy of artificial intelligence-designed dental crowns: a scoping review of in-vitro studies. Appl. Sci. 2025, 15, 9866. [Google Scholar] [CrossRef]
- Colton, S.; Wiggins, G.A. Computational creativity: The final frontier? Front. Artif. Intell. Appl. 2012, 242, 21–26. [Google Scholar]
- Sajjadi, M.S.M.; Bachem, O.; Lucic, M.; Bousquet, O.; Gelly, S. Assessing generative models via precision and recall. Adv. Neural Inf. Process. Syst. 2018, 31. [Google Scholar]
- Heusel, M.; Ramsauer, H.; Unterthiner, T.; Nessler, B.; Hochreiter, S. GANs trained by a two time-scale update rule converge to a local Nash equilibrium. Adv. Neural Inf. Process. Syst. 2017, 30. [Google Scholar]
- Achlioptas, P.; Diamanti, O.; Mitliagkas, I.; Guibas, L. Learning representations and generative models for 3D point clouds. Proc. 35th Int. Conf. Mach. Learn. 2018, 80, 40–49. [Google Scholar]
- Karras, T.; Laine, S.; Aila, T. A style-based generator architecture for generative adversarial networks. In Proceedings of the IEEE/CVF Conference on Computer Vision and Pattern Recognition; 2019; pp. 4401–4410. [Google Scholar]
- Brock, A.; Donahue, J.; Simonyan, K. Large scale GAN training for high fidelity natural image synthesis. In Proceedings of the International Conference on Learning Representations; 2019. [Google Scholar]
- Betzalel, E.; Penso, C.; Fetaya, E. Evaluation metrics for generative models: an empirical study. Mach. Learn. Knowl. Extr. 2024, 6, 1531–1544. [Google Scholar] [CrossRef]
- Wang, C.; Peng, H.Y.; Liu, Y.T.; Gu, J.; Hu, S.M. Diffusion models for 3D generation: a survey. Comput. Vis. Media 2025, 11, 1–28. [Google Scholar] [CrossRef]






| Prosthetic field (input information) | Compared pair of designs | HD results | ||
| Mean HD | Max HD | RMS | ||
| №1 | 1 vs 2 | 1.12 | 12.20 | 1.84 |
| 1 vs 3 | 3.87 | 17.26 | 4.96 | |
| 2 vs 3 | 4.31 | 16.20 | 5.35 | |
| №2 | 1 vs 2 | 1.32 | 16.40 | 2.42 |
| 1 vs 3 | 4.00 | 14.98 | 5.01 | |
| 2 vs 3 | 4.13 | 14.35 | 5.16 | |
| №3 | 1 vs 2 | 1.08 | 12.40 | 1.87 |
| 1 vs 3 | 4.89 | 18.49 | 6.26 | |
| 2 vs 3 | 5.14 | 23.32 | 6.74 | |
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