Submitted:
22 April 2026
Posted:
23 April 2026
You are already at the latest version
Abstract
Traumatic tracheal injuries and congenital defects can be life threatening. Regenerating the trachea through tissue engineered scaffolds has emerged as an innovative alternative to traditional therapies. At present time, challenges in tracheal regeneration preclude clinical adoption, such as revascularization and promotion of favorable paracrine and immune signaling responses. This review summarizes current advances in tracheal regeneration and highlights key biological and engineering barriers to address to achieve functional tracheal regeneration.
Keywords:
tracheal tissue enginneering
; tracheal regeneration
; advancements
; barriers
Copyright: This open access article is published under a Creative Commons CC BY 4.0 license, which permit the free download, distribution, and reuse, provided that the author and preprint are cited in any reuse.
