Background: This study aims to psychometrically validate the abbreviated version of the Connor-Davidson Resilience Scale (CD-RISC-10) in Peruvian nurses, evaluating its convergent validity through its association with perceived stress and empathy. Methods: A cross-sectional psychometric study was conducted in 374 Peruvian nurses to evaluate the psychometric properties of CD-RISC-10 through confirmatory factor analysis (CFA). In addition, convergent validity was examined by correlational analysis with Spearman's ρ coefficient with empathy and resilience. Results: The CFA confirmed that the one-dimensional model has a good fit (CFI = 0.978, TLI = 0.971, RMSEA = 0.080, and SRMR = 0.044). Cronbach's alpha of 0.89 and McDonald's omega of 0.81 were obtained. Convergent validity showed significant correlations with perceived stress (ρ = -0.23, p < 0.001) and empathy (ρ = 0.31, p < 0.001). Conclusion: The CD-RISC-10 has excellent psychometric properties in Peruvian nurses. Future studies are needed to evaluate their factorial invariance between clinical specialties and determine cut-off points.