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Perceived Barriers and Facilitators to Physical Activity Engagement Among Cancer Survivors: A Qualitative Study

Submitted:

09 January 2026

Posted:

12 January 2026

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Abstract
Background: Although physical activity (PA) offers substantial physical and psychosocial benefits, engagement remain suboptimal among cancer survivors. A theory-informed understanding of survivors’ perceived barriers, facilitators, and recommendations is needed to inform patient-centered PA survivorship interventions. Objective: This study aimed to explore perceived barriers, facilitators, and recommendations for PA engagement among adult cancer survivors using the Theoretical Domains Framework (TDF). Methods: A phenomenological qualitative design was used. Eighteen cancer survivors from Nebraska participated in semi-structured interviews via Zoom or telephone. Interviews were transcribed verbatim, imported into MAXQDA 2024, and analyzed using TDF to identify themes and subthemes. Results: Three overarching themes emerged: barriers, facilitators, and recommendations related to PA engagement. Barriers included individual factors (low motivation and self-efficacy, limited awareness of PA guidelines, time constraints, and physical limitations due to treatment and comorbidities), social factors (limited support from family, friends, and healthcare providers), and environmental factors (restricted access to resources and unfavorable weather). Facilitators included individual factors (PA knowledge, motivation, goals, and health benefits), social factors (support from family, friends, and healthcare providers), and environmental factors (favorable weather and available community PA resources). Recommendations emphasized the need for tailored education, supportive counseling, and structured PA programs within survivorship care. Conclusions: Cancer survivors described multilevel determinants of PA engagement across individual, social, and environmental contexts. Findings highlight the importance of theory-informed, patient-centered strategies that enhance PA guideline awareness, strengthen social and clinical support, and improve access to community resources to promote sustained PA during cancer survivorship.
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1. Introduction

Cancer is a significant public health concern in the United States, ranking as the second leading cause of mortality and presenting substantial challenges to modern medicine [1,2]. In 2025, an estimated 2,041,910 new cancer cases and 618,120 cancer deaths are projected in the United States [1]. Due to advances in screening and treatment, survivorship has increased substantially, with approximately 18.6 million individuals currently living with a history of cancer, a number projected to exceed 22 million by 2035 [1]. As survivorship continues to rise, there is increasing recognition of the need to address long-term and supportive care needs across the survivorship continuum [3,4,5,6].
Despite advancements in cancer prognosis, a substantial proportion of cancer survivors continue to experience persistent, or late-onset effects related to cancer and its treatment. These include fatigue, anxiety, depression, peripheral neuropathy, and declines in strength and cardiorespiratory fitness, all of which can negatively impact daily functioning and the overall quality of life [7,8,9]. Survivors are also at an elevated risk for comorbid conditions, such as cardiovascular disease, osteoporosis, and musculoskeletal impairments, further contributing to the long-term health burden and increased healthcare utilization [10,11]. These cumulative effects highlight the importance of supportive strategies that promote physical and emotional well-being during the survivorship phase.
In addition to their physical and emotional effects, cancer and its treatment impose a significant economic burden. The overall national cost of cancer care in 2015 was estimated at $183 billion and is projected to increase by 34% to $246 billion by 2030, based solely on population growth [12]. These rising costs are compounded by billions of dollars in productivity losses due to disabilities, unemployment, and reduced household productivity [13,14]. Consequently, there is a growing emphasis on modifiable lifestyle behaviors, such as physical activity (PA), which can aid in both cancer prevention and survivorship [15,16,17,18]. This paradigm shift from disease-centered treatment to holistic wellness-oriented care highlights a critical opportunity for oncology care providers (OCPs) and researchers to promote and support healthy lifestyle behaviors among cancer survivors [19,20,21,22].
The American Cancer Society and the American College of Sports Medicine recommend that cancer survivors engage in 150-300 minutes of moderate-intensity or 75-150 minutes of vigorous-intensity PA per week, along with muscle-strengthening activities at least twice weekly, tailored to individual needs and health status [23,24]. Extensive evidence demonstrates that PA reduces treatment-related side effects, improves fatigue, mental health, and quality of life, enhances physical function, and reduces recurrence and mortality risk [7,23,25,26]. However, most cancer survivors do not achieve the recommended PA levels, with estimates indicating that fewer than half achieve the recommended PA targets [27,28]. This gap highlights the urgent need to better understand the factors influencing PA engagement among cancer survivors.
Prior research has identified several barriers related to PA among cancer survivors, including treatment-related symptoms, limited guidance from healthcare providers, lack of tailored resources, and challenges with motivation and confidence [22,29,30,31]. However, much of the existing evidence comes from survivors participating in structured lifestyle or exercise interventions, often within academic or clinical settings [32,33], where participants may already be motivated to engage in PA. Consequently, the findings may not fully reflect the experiences of the broader survivor population , particularly those navigating PA outside of structured programs or formal clinical environments. In addition, survivors’ knowledge of PA guidelines and the broader individual, social, and environmental contexts shaping PA engagement have received limited attention, suggesting a limited understanding of how survivors navigate PA in their daily lives [31]. Importantly, several prior studies have not been grounded in a guiding theoretical framework, restricting the understanding of how psychosocial, behavioral, and environmental factors interact to influence PA behavior across the survivorship continuum [17,34,35].
To address these gaps, the present study recruited cancer survivors from community-based settings rather than structured exercise or clinical intervention programs and incorporated the Theoretical Domains Framework (TDF), a comprehensive framework synthesizing constructs from 33 behavior change theories [36,37], to examine multilevel determinants of PA among cancer survivors. Using a qualitative approach, this study explored the perceived barriers, facilitators, and recommendations for PA engagement among cancer survivors through the lens of the TDF, thereby providing a theory-informed, contextually grounded understanding of the behavioral and environmental influences that shape PA participation in cancer survivorship.

2. Methods

2.1. Study Design

This study utilized a phenomenological qualitative design to obtain in-depth insights from cancer survivors regarding their perceptions of the barriers to and facilitators of engaging in PA and their recommendations. Phenomenology emphasizes the exploration of lived experiences and the meanings individuals ascribe to those experiences [38]. Anchored in a social constructivist paradigm, this study sought to understand how participants interpreted their experiences within broader sociocultural and historical contexts [39]. An iterative, interpretive approach was used to capture the participants’ perspectives and develop a comprehensive understanding of their lived experiences [40]. Ethical approval was obtained from the Institutional Review Board (of the University of Nebraska Medical Center (IRB# 0468-23-EX).

2.2. Sampling and Recruitment

Participants were recruited using purposive and snowball sampling methods to capture diverse perspectives. The eligibility criteria were as follows: (i) age ≥19 years, (ii) self-identification as a cancer survivor, (iii) ability to speak and understand English, and (iv) residence in Nebraska. A cancer survivor was defined as an individual with a cancer diagnosis and alive at the time of the study (Denlinger et al., 2014). Participants were excluded if they (i) did not have a cancer diagnosis, (ii) were not residents of Nebraska, or (iii) had cognitive impairment or severe psychiatric conditions that could affect their ability to provide informed consent or meaningfully participate. Efforts were made to ensure diversity in terms of cancer type, age, sex, and race to capture a wide range of opinions, reflecting the experiences of a larger survival community rather than narrowing our insights into a specific sub-group. The planned sample size for the study was 18 cancer survivors. Previous research has shown that 8 to 16 in-depth interviews provide 80-90% data saturation [41]. In the present study, data saturation was reached after 16 interviews; however, two additional participants were interviewed because they had already expressed interest and met eligibility criteria. The inclusion of these participants ensured that all interested and eligible voices were represented, and confirmability and depth were added to the thematic analysis.
Recruitment was conducted by sharing a digital flyer with clinical and community partners, including oncology clinics, hospitals, support groups, and survivorship programs, as well as through social media, e-mail distribution, and participant referrals. The flyer provided a brief overview of the study, eligibility criteria, contact information, and a QR code linking to an online screening survey administered through Qualtrics. Individuals who completed the screening survey and met the eligibility criteria were contacted by the principal investigator (GK) through their preferred method of communication (e.g., text, email, or phone call) to schedule an interview. Semi-structured interviews were conducted via Zoom at a date and time that was convenient for each participant. A total of 18 cancer survivors were interviewed between August 2023 and January 2024.

2.3. Data Collection

The interviews were conducted by the principal investigator (GK), who has approximately nine years of experience conducting qualitative interviews through graduate-level training and prior research, and received additional mentorship from a faculty advisor (DS), who had over 15 years of qualitative research experience. To evaluate the clarity and relevance of the interview guide and estimate the interview duration, a cognitive interview technique (“think-aloud”) was utilized [42]. Two pilot interviews were conducted prior to data collection, after which minor revisions were made to improve question clarity, for example, explicitly defining the term physical activity (to avoid confusion with the term exercise) and removing redundant items.
Prior to each interview, a consent form outlining the study’s purpose and procedures was emailed to the participants, and verbal consent was obtained at the start of the interview. To minimize social desirability bias, the interviewer built rapport and used probing strategies when the responses appeared overly positive, simplified, or socially influenced [43,44]. Participants’ sociodemographic and cancer history questions included age, gender, educational level, cancer type, and cancer treatment. A detailed list of questions is provided in supplementary file (see Appendix A). The interviews ranged from 20 to 60 minutes (mean = 40 minutes) in length. Participants received a $50 prepaid Visa gift card as compensation, supported by the University of Nebraska Medical Center College of Public Health Sparks Student Research Award.

2.4. Semi-Structured Interview

The interview guide was developed using Theoretical Domains Framework (TDF) version 1 and reviewed by a senior author (DS). TDF v1 synthesizes constructs from 33 behavior-change theories (128 constructs) into the following 12 domains: knowledge; skills; social/professional role and identity; beliefs about capabilities; beliefs about consequences; motivation and goals; memory/attention and decision processes; environmental context and resources; social influences; emotion; behavioral regulation; and nature of the behavior. Each question mapped to at least one TDF v1 domain (see supplementary file-Appendix B) to ensure comprehensive coverage of hypothesized determinants of PA behavior among survivors Although later refinements expanded the TDF to 14 domains, including “optimism” and “reinforcement,” this study explicitly applied the 12-domain v1 because it aligned more closely with the study’s research questions and focus on identifying cognitive, emotional, social, and environmental determinants of physical activity among cancer survivors. The TDF has been validated for behavioral and implementation research and is widely used in qualitative analyses [36].

2.5. Data Analysis

The interviews were audio-recorded, professionally transcribed verbatim, and de-identified prior to analysis. The transcripts were uploaded into MAXQDA 2024 (VERBI Software, Berlin, Germany) for data management and analysis. Data were analyzed using a deductive-inductive thematic analysis approach. Although the TDF informed the development of the interview guide (deductive), coding and theme development were conducted inductively, allowing themes to emerge directly from participants’ narratives rather than being constrained by predefined theoretical categories.
This study employed thematic analysis while drawing on principles of framework analysis, following the five iterative steps outlined by Gale and colleagues [45] : (1) familiarization with the data, (2) identifying an initial coding framework, (3) indexing transcripts systematically, (4) charting data into thematic matrices, and (5) mapping and interpreting patterns across participants. The principal investigator (GK) read each transcript multiple times to gain immersion and identify significant statements that captured key meanings. These statements were grouped and compared across transcripts to identify recurring patterns and develop preliminary categories for analysis.
To ensure study rigor, credibility, and trustworthiness, we incorporated peer debriefing and triangulation throughout the analytic process. [46]. A preliminary codebook was initially informed by broad topic areas from the semi-structured interview guide; however, during coding, new codes were added inductively based on participant responses, allowing the codebook to be refined. Two researchers (GK and PC) independently coded five randomly selected transcripts (~25% of the dataset) and compared the coding decisions to assess consistency. Discrepancies were discussed until a consensus was reached, after which the principal investigator (GK) continued coding the remaining transcripts.
Throughout the coding process, analytic memos and an audit trail were maintained to support transparency and reflexivity [47]. After coding was completed, themes and subthemes were identified, refined, and organized to represent coherent patterns in the participants’ experiences. Direct quotations were selected to illustrate the thematic interpretation [48]. Themes were then mapped back to the relevant domains of the TDF during the interpretive phase, providing a theoretical context while preserving the inductively generated nature of the findings. This study followed the Standards for Reporting Qualitative Research (SRQR) framework [49].

3. Results

3.1. Sample Characteristics

Overall, 18 cancer survivors participated in the semi-structured interviews (Table 1). More than two-thirds of the participants were female and married, and half were non-Hispanic whites. The mean age at cancer diagnosis was 60.2 years (SD ± 11.4). The cancer diagnoses included a variety of types, with breast cancer being the most common (44.6%). Cancer stages ranged from I to IV, with half being stage III, and treatments included surgery, adjuvant and neoadjuvant chemotherapy.

3.2. Qualitative Findings

Guided by the 12-domain TDF v1[36], thematic analysis revealed three overarching themes: barriers, facilitators, and recommendations, which encompassed multiple behavioral determinants of PA among cancer survivors. These themes reflected a dynamic interaction among individual, social, and environmental influences and aligned with all twelve TDF domains (Table 2).

3.3. Theme 1. PA Barriers Faced by Cancer Survivors

Qualitative data analysis revealed three subthemes: individual, social, and environmental barriers, each encompassing specific challenges faced by cancer survivors.

3.3.1. Individual-Level PA Barriers

Cancer survivors often face distinct challenges in engaging in regular PA. Their participation is hindered by a complex interplay of barriers, such as a lack of motivation, limited awareness of PA guidelines specific to their health needs, and time constraints. Moreover, persistent physical limitations, such as pain, fatigue, and treatment-related side effects, can further diminish their capacity and confidence to be active. Collectively, these barriers can make it daunting for survivors to initiate or maintain regular physical activity.
Lack of Motivation and self-efficacy as barriers to PA: Several participants described a persistent lack of motivation to engage in PA, often linked to the overwhelming physical and emotional burden of cancer treatment. Survivors frequently reported feeling fatigued or disinterested in engaging in activities beyond managing their daily routines. As one participant shared: “Most of the time, I get lazy… I am not motivated.” Another acknowledged having access to exercise resources but struggled to use them, stating, “We have a treadmill and a recumbent bicycle in the basement. They’re there-I just need to use them.” Several participants recognized internal resistance as a primary barrier, with one noting, “What prevents me sometimes is myself—just not wanting to do it.”
Limited awareness of PA guidelines: A substantial knowledge gap emerged among participants regarding awareness of PA guidelines for cancer survivors. Many acknowledged a lack of familiarity with any formal recommendations, often responding with uncertainty when asked about the PA guidelines. Several participants simply responded, “No, I don’t know,” reflecting a widespread lack of exposure to standardized information. Some survivors described relying on self-directed approaches to wellness rather than evidence-based guidance. As one survivor noted, “No, I have my own recommendations I follow. So, I don’t know.”
Competing demands and limited time as barriers to PA: Time emerged as a major barrier to engaging in PA, with some survivors describing the challenge of balancing professional, familial, and personal responsibilities. Several participants emphasized how work commitments frequently disrupted their exercise routines. One survivor reflected on how professional demands disrupted their intentions to stay active: “Perhaps my schedule at work-sometimes I have to stay late for meetings or other things that hinder my schedule. Then I can’t do the walking that I intend to do. Scheduling can be a hindrance.” Another participant, managing multiple roles, expressed similar difficulty in prioritizing exercise amid daily obligations: “It’s just time because I work full time. I’m a single parent, and I have a part-time job every other weekend.”
Physical limitations from treatment side effects and comorbidities: Participants frequently described enduring physical challenges arising from cancer treatment side effects and coexisting health conditions that limited their ability to engage in PA. Chemotherapy-related symptoms such as pain, bloating, and fatigue were frequently reported: “Chemotherapy was really hard for me. I couldn’t walk without pain. My feet were bloated. There were days I did not get out of bed.” Another participant noted persistent pain and fatigue, “I do less activity now due to fatigue and muscle aches and pains.” Neuropathy also emerged as a significant barrier, with one survivor expressing, “The neuropathy in my feet has made me fear falling during physical activity.” Surgical limitations were evident: “I had one of the lobes of my lung removed, so I get out of breath easily. That limits me.” Additionally, comorbid conditions compounded restrictions “I have a hernia now… trigger fingers on my dominant hand… there’s been a lot of limitations.”

3.3.2. Social-Level PA Barriers

Social barriers highlight the importance of a supportive network in facilitating PA among cancer survivors. The lack of social support from family, friends, and oncology care providers can significantly diminish their motivation and opportunities for engaging in PA.
Limited social and clinical support in PA engagement: Most cancer survivors described a lack of encouragement and companionship from family and friends as a significant barrier to maintaining regular PA. Some participants expressed feelings of isolation, noting an absence of shared motivation or social accountability. For example, one participant shared, “I really don’t have anybody… I always say I’m alone, but I’m not lonely,” reflecting the emotional solitude of survivorship. The absence of companionship was a recurring theme “I don’t have anyone that says, ‘Come on, let’s go for a walk or a jog.’” Relocation and disrupted social networks further compounded this challenge, as one survivor described, “I don’t have many friends in Omaha yet… we moved here two years ago, and I don’t know anybody because of cancer treatment.”
Limited PA guidance from the oncology care providers: Cancer survivors described receiving limited or nonspecific guidance from their oncology care teams regarding PA following treatment. Several survivors noted that discussion about exercise was either absent or too general to be actionable. One participant stated, “Not for my cancer,” highlighting a lack of tailored advice. Another shared, “Not directly from my healthcare providers-they kind of mentioned it would be a good idea, but there was no specific guidance.” Limited time during clinic visits further compounded this issue, as reflected by one participant who said, “I saw an oncologist… but only for five minutes. They’re so busy; they don’t have time to talk to me (about PA).” The emotional impact of this absence of support was profound, as one expressed, “I think they just want to give you a blanket and tell you to lay down the rest of your life.” Missed referrals to supportive programs were also evident: “She never said anything about the YMCA Livestrong program or the American Cancer Society,” underscoring missed opportunities to connect survivors with beneficial PA resources.

3.3.3. Environmental-Level PA Barriers

Environmental barriers present additional obstacles to PA among cancer survivors. Accessibility issues, such as the limited availability of parks, trails, and safe sidewalks and concerns about safety, finances, and transportation, can restrict their ability to engage in outdoor activities.
Limited accessibility as barriers to PA resources: Cancer survivors frequently cited a range of environmental and resource-related limitations that hindered their ability to engage in regular PA. A lack of safe, pedestrian-friendly infrastructure was a common concern with one participant noting, “There are no sidewalks where I live… But that will never happen there.” Others emphasized how distance and traffic limited their access to fitness facilities difficult, as one participant noted, “I wish the YMCA was closer. I don’t like to drive in Omaha traffic.” Financial barriers added to the challenge “I got a scholarship for a year because I was in LIVESTRONG, but $70 a month was a bit much after paying all these medical bills.” Additionally, the discontinuation of suitable exercise classes frustrated some survivors who made efforts to integrate PA into their schedules, “On the day that I made time to do the total body conditioning… they don’t offer that class anymore.” Safety concerns, particularly for women, further restricted outdoor activity options: “There’s a park not too far from our house… I don’t know if I feel safe to go there,” and “I wouldn’t walk far at night; in the winter it gets dark sooner. I’m more careful then, especially as a woman.”
Weather and seasonal conditions as barriers to PA: Weather emerged as a prominent environmental barrier that limited cancer survivors ability to maintain consistent regular PA throughout the year. Harsh winters characterized by ice, snow, and cold temperatures often discourage outdoor activities. One participant noted, “Winter, you know—ice, snow, those kinds of things… that would prevent somebody from enjoying a few hours on a bicycle outside.” Others described avoiding activity during extreme cold: “If it’s just been too cold, I don’t want to walk around when the air hurts my face.” Conversely, high temperatures also posed significant challenges, especially for those managing treatment-related heat sensitivity or medication restrictions: “The weather-it was so hot, hot flashes. I can’t walk in the heat,” and “I don’t do too well in heat… I’m not supposed to be out in the sun too long.” Many participants summarized the struggle as a year-round challenge, with one stating, “Welcome to Nebraska! We’re very limited… more active in spring and summer, less in fall and winter. The weather has a lot to do with it.”

3.4. Theme 2. Facilitators of PA

While numerous barriers hindered consistent PA among cancer survivors, several facilitators emerged that enabled engagement and sustained participation. These facilitators spanned individual, social, and environmental levels.

3.4.1. Individual-Level Factors

Adequate knowledge-related PA: Cancer survivors described PA in diverse and personally meaningful ways, reflecting variations in how they conceptualized movement and PA. For some, it meant “just staying active over time, as much as possible,” emphasizing consistency over intensity. Others associated it with specific recreational or outdoor activities like “bicycling, walking, hiking, and alpine skiing.” Survivors also highlighted both structured and everyday movements from “going to the gym and working out with weights and running” to “dancing, walking, or even yard work and vacuuming.” Many viewed PA as any action that kept them engaged and out of sedentary routine, noting, “Not sitting… leaving the house? Running errands?” This broad understanding underscored that PA extended beyond formal exercise to include daily routines and leisure activities, with one participant summarizing: “It’s not about sweating in the gym-it’s about walking around the park, just getting my heart rate up a little bit.”
Motivation for PA: Cancer survivors described strong intrinsic motivation driven by both emotional and physical rewards. Many highlighted the uplifting effects of PA, noting, “It makes me feel really good… everything is just better,” emphasizing improved mood and overall well-being. Commitment to routine was also important “At least 30 minutes… I try not to skip Saturday and Sunday” reflecting the role of consistency in maintaining activity. Several participants expressed determination despite barriers, saying, “I make time no matter what” and “I just try to stay busy, a lot of outdoor stuff.” For others, surviving cancer itself served as a powerful motivator: “Being alive has made me want to step up since I’ve conquered a lot of the challenges with cancer.”
Goals for PA: Cancer survivors described a wide range of PA goals reflecting different recovery stages and priorities. Some focused on small daily achievements such as “drink water, get out of bed, go downstairs,” while others aimed for more structured routines like “walk five miles, go to the gym three times a week, and do yoga.” Quantifiable goals were also common: “Typically, those goals are 75 miles of biking per week and 10,000 steps per day.” Several survivors emphasized self-accountability “I signed a contract with myself that I would try to walk a 5k every month.” Others expressed a desire to regain former fitness levels, saying, “I’d like to improve my endurance as I used to… I’d love to do that again.”
Perceived Health Benefits of PA: Cancer survivors described that engaging in PA played as essential role in facilitating both physical and mental recovery. Many participants reported that regular PA improved their strength, energy, and resilience against treatment effects. One participant shared, “It makes you healthier to fight cancer,” while another emphasized, “Anytime your physique is optimal…your blood is flowing, your heart is pumping…you’re a stronger person.”
The mental health benefits of regular PA were equally prominent where survivors mentioned how PA contributed to emotional stability, enhanced mood, and psychological well-being. One participant noted, “It helped me because I just feel good,” and “It’s also helped my mental health.” Several credited endorphins for fostering positivity and healing, noting, “If you’re happy, you release endorphins, I think they have healing power.”
Beyond immediate improvements, many survivors connected PA to effective symptoms management and long-term health outcomes. Participants described PA as essential for managing symptoms specific to their cancer experience. One explained, “Having cancer in the lungs, I feel that keeping my lungs moving will help me in the long run.” while others highlighted the broader implications of regular PA, shaping beliefs that it contributed to reduced risk of recurrence and extended survival. another reflected, “It helps with health outcomes, reducing recurrence, and living longer.”

3.4.2. Impact of Social Support on PA

Social support emerged as a significant facilitator of physical activity among cancer survivors, influencing motivation, consistency, and overall well-being through various relationships and channels
Family members emerged as a key facilitator of PA among cancer survivors, providing encouragement, companionship, and practical assistance. Many survivors described family involvement as both inspirational and participatory. One shared, “I ride a bicycle with my uncle once a week… my 80-year-old uncle and I ride 20 miles in a week,” reflecting both support and shared commitment. While another drew motivation from daily gestures, one said, “My wife supports me and participates. When I leave in the morning, she always tells me she’s proud of me for getting up and going.”
Partners who were physically active often served as role models, encouraging shared pursuits such as walking or hiking, and some benefited from expert advice within the family. One participant said, “My sister is a professional bodybuilder, and her husband, a personal trainer, always says I need to do weights every day.” Others mentioned tangible support, such as help purchasing exercise equipment, indicated the practical ways family fosters PA, “My husband’s the one who said we needed to buy that exercise bike.”
Friends and co-workers were valued as vital sources of companionship, motivation, and accountability for engaging in PA, alongside family support. Social interactions often transformed PA into an enjoyable and therapeutic experience as one survivor shared, “A neighbor actually invited me to go for walks. We started slowly, and not only were we walking, we were talking, so it was almost like our physical and mental therapy.” Another emphasized the joy of shared activity, “When I was walking with friends, it was very enjoyable because I really liked her company… we both felt great and looked forward to the next day.”
Further, coworkers were also mentioned as motivators: “I have a really good friend here at work. He’s starting to exercise as well. And we just have the camaraderie back and forth to motivate each other.” Participants in group activities and yoga communities also provided ongoing encouragement and accountability, “There’s a group of women, and if you miss too many weeks, they ask, ‘Where were you?’” and “I have a great yoga Sangha community that sent me videos when I was in treatment.”
Oncology care providers were another factor in facilitating PA, as cancer survivors, benefited from personalized recommendations and encouragement tailored to each survivor's unique condition and capabilities. One participant shared, “The oncologist said walking would be my best physical activity,” highlighting the practical guidance received. Another noted, “She (oncologist) was encouraging water aerobics for my right arm and just like being gentle. She really encouraged the gentle water aerobics yoga.”
Finally, a few survivors mentioned their pets as meaningful motivators for staying active. As one stated, “I love taking my dog for walks.”

3.4.3. Environmental Factors

Environmental factors played an important role in shaping cancer survivors’ ability to engage in physical activity, with weather conditions and the availability of community resources emerging as key facilitators of participation.
Weather: Cancer survivors described how weather conditions can serve as a significant facilitator for engaging in PA, indicating the appeal of outdoor environments during pleasant conditions. Many described how favorable weather encourages participation in activities such as walking in local parks, with one survivor noting, “My husband and I go to the park that's real close to our house, and we work the walking trail there in the summertime and when weather is favorable." The enjoyment of spending time outdoors was further reflected by another survivor who found both joy and engagement in gardening during nice weather: "That's the good thing when it is nice, I like to be outside. I had a garden outside. I mean, it's nice to go out and, you know, tend to my flowers in the garden." Survivors also discussed adapting PA to the seasonal changes and less favorable conditions. When outdoor walking or running was less practical due to cold or snowy weather, participants found alternative ways to stay active such as raking leaves and shoveling snow. As one participant noted, "But when it snows around here, or when it's fall time, I'm raking leaves or helping to shovel snow. So, there's always something that needs to be done."
Availability of PA resources in the community: Cancer survivors emphasized the value of accessible community resources in supporting and motivating their participation in PA. Programs such as the YMCA’s LIVESTRONG program and Time to Heal were frequently praised for providing structured support tailored to survivors needs. . One survivor shared, “Yes, I’ve gone to the YMCA, and they have a Livestrong program. And that was amazing.” Survivors also appreciated the diversity and affordability of options available within their community, noting, “The YMCA actually offers very affordable personal training and a ton of different programs,” emphasizing accessibility and adaptability. In addition to these programs, other resources, including SilverSneakers and local facilities such as the generation center, were also mentioned as sources of motivation and regular encouragement. As one survivor described, “I joined SilverSneakers, so they send regular emails with how important physical activity is, and they recommend (PA), you know, by age group, male, female, kids, like how much and for how long.”

3.5. Theme 3. Recommendations to Enhance PA Engagement

Cancer survivors provided practical recommendations to enhance PA participation, emphasizing the importance of enjoyable and accessible activities, stronger educational and community support, and more personalized guidance from oncology care providers.
Cancer survivors: Cancer survivors emphasized the importance of simple, accessible, and enjoyable forms of PA, particularly walking, as effective and manageable strategies to maintain health and support recovery. One participant shared, “Walking is one of the best, easiest ways to exercise-you don’t need to join a gym, just walk every day.” Survivors also mentioned the role of enjoyment and social motivation in sustaining engagement, with advice such as “Keep moving, get in a group that motivates you, and have fun-the biggest part is to have fun doing it.” In addition to these motivational factors, survivors expressed a strong need for expanded educational and community resources to support their ongoing PA effort, asking for “more pamphlets, more information, more support groups,”. Structured and community-based programs like the YMCA LIVESTRONG initiative were highly valued for their tailored approach and affordability: “I’d really recommend the YMCA LIVESTRONG program-it’s awesome that they offer that for free.”
Oncology care providers: Cancer survivors emphasized the critical need for oncology care providers to offer more personalized and proactive guidance on PA as part of holistic components of comprehensive cancer care. Survivors expressed the desire for clear, practical advice tailored to their unique health needs: “I think you’re more likely to get guidelines from your oncologist-to say, don’t do this activity, but it’s okay to do that one.” The value of group-based recommendations was highlighted as a means to boost motivation and provide social support, as one noted, “I wish they would tell people to join a group setting where they can have friends to keep them motivated.” Several participants highlighted missed opportunities for referral to existing programs, such as the YMCA’s LIVESTRONG initiative: “They never even mentioned the YMCA LIVESTRONG program… every oncology doctor should mention that to every patient.” Survivors further suggested the importance of initiating conversations about PA should begin early in treatment “Maybe if it was brought up sooner while I was going through chemo, that would help more”.

4. Discussion

To our knowledge, this is among the first qualitative studies conducted in the U.S. Midwest to apply the TDF in exploring cancer survivors’ perspectives on barriers, facilitators, and recommendations for PA. This study provides valuable insights into the multilevel factors such as individual, social, and environmental that shapes PA behaviors among survivors. The findings underscore the complex and interdependent nature of these influences, highlighting how personal motivation, social support, and environmental accessibility collectively determine survivors’ ability to engage in and sustain PA participation.
At the individual level, participants identified major barriers, including a lack of motivation, limited awareness of PA guidelines, time constraints, and physical limitations associated with treatment side effects and comorbidities. These findings are consistent with prior research demonstrating that cancer survivors face distinctive challenges in maintaining physical activity, despite its known benefits for recovery and long-term survivorship [27,50]. The pervasive lack of motivation aligns with previous work [31,51,52] and appears to be driven largely by fatigue and emotional exhaustion resulting from cancer treatment. Evidence suggests that interventions incorporating motivational interviewing and goal setting can effectively enhance engagement and activity levels [53,54]. Moreover, digital health technologies such as mobile apps and wearable devices could offer continuous feedback and individualized support, potentially mitigating motivational barriers [55,56].
Our study showed a notable lack of knowledge about PA guidelines for cancer survivors, consistent with the findings of previous studies [50,57,58], which highlighted a general lack of awareness and comprehension of these guidelines. Targeted educational initiatives that provide clear, accessible, and customized PA information are crucial to bridging this gap [24,59]. These programs must be incorporated into survivorship care plans and endorsed by cancer care professionals, who have a vital role in spreading this knowledge [22]. Moreover, developing patient-centric materials like easy-to-navigate websites or pamphlets with precise PA guidelines for cancer survivors could help reduce information-related barriers [24,60].
Cancer survivors face difficulty finding time for PA due to work and family responsibilities, coherent with other research studies [27,50,61,62]. To overcome this obstacle, it is necessary to implement adaptable and customized strategies that align with the survivors' current schedules and obligations [63]. Implementing strategies like time management workshops, adaptable exercise regimens, and encouraging brief periods of PA during the day can provide practical solutions. Employer-backed programs offering flexible work hours or wellness efforts could help reduce time-related obstacles for employed survivors [64,65].
Cancer survivors sometimes face significant challenges to engaging in PA due to physical restrictions such as pain, exhaustion, and treatment side effects. The results align with recent studies [17,27,31,50], which emphasized the influence of physical side effects on activity levels. Rehabilitation programs that include physical therapy, pain management, and adaptive PA interventions are crucial for overcoming these obstacles [66,67]. It is essential to create fitness programs that cater to the unique physical restrictions of cancer survivors, including low-impact workouts and personalized strength training [17,24,32,66,67,68].
At the social level, the study underscores the vital role of family, friends, and healthcare providers in promoting PA. Many participants described limited encouragement from family or friends, often leading to feelings of isolation. This aligns with existing research, emphasizing that the quality of social interactions is critical for sustaining engagement in PA [69,70]. Similarly, inadequate support from oncology care providers mirrors earlier findings [22,58,71], underscoring the need for consistent PA counseling within oncology and survivorship care. Participants’ perception that the transition to survivorship lacked sufficient guidance highlights the importance of integrating structured discussions on PA early in the care continuum.
Obstacles related to the environment include difficulties in accessing outdoor activities, financial limitations, and weather-related hindrances. Access to safe and convenient places for PA, such as parks, trails, and fitness centers, is a significant obstacle. As criticized by survivors, the absence of pedestrian-friendly infrastructure highlights a larger problem in urban planning and community design that does not promote active lives [72]. Distance and transportation issues may hinder access to fitness centers, which can discourage consistent PA [35,50,61]. Financial difficulties worsen this issue, as the expense of a gym membership becomes a considerable burden, particularly when combined with increasing medical expenses [27,73].
Safety concerns, particularly in public spaces or at night, significantly affect cancer survivors' willingness to participate in outdoor physical activities [27,72,74]. These challenges are particularly noticeable for women and underscore the importance of having safe, well-lit, and easily accessible areas for PA [75]. Implementing community watch programs and enhancing lighting in public parks and trails can improve safety perceptions. Organizing group walks or exercise classes in public spaces might improve emotions of safety and community, as suggested by previous studies [69,72,75].
Harsh temperatures and severe weather conditions pose significant challenges to outdoor PA. These challenges are particularly evident in regions with varying temperatures, where seasonal changes can significantly affect the feasibility of outdoor exercise [50,72]. Supporting and broadening indoor PA choices, such as mall walking programs or indoor swimming, can provide alternatives during extreme weather conditions [76]. Developing exercise routines adapted to various weather conditions, including online or home-based options, can support the continuity of PA throughout the year [77,78].
Strengths and Limitations
One strength of this study is the systematic approach used in data collection and analysis to enhance the reliability and validity of the analysis: checking transcripts against audio recordings and field notes taken, and triangulation among coders by consensus to ensure rigor. Purposeful sampling was used to select a wide range of providers with different experiences. We chose one-on-one interviews to focus on each participant’s ideas and experiences during the interview. This strategy was adopted to ensure that individuals’ distinctive viewpoints were not impacted by the dynamics of group debates or worries about their ideas being regarded as ‘incorrect’ by others [79].
Despite its strengths, this study had several limitations that should be considered when interpreting the findings. First, the sample included only cancer survivors from one Midwestern state. Therefore, the findings may not be transferable to cancer survivors in different regions of the United States and other countries, as PA behavior may vary. Additional research is needed to determine whether these findings can be replicated elsewhere. Social desirability bias should be acknowledged, as cancer survivors may have responded to appease the researchers. However, steps were taken to reduce biases by establishing rapport before the interviews, asking probing questions, and noting whether participants gave potentially socially desirable responses.

5. Conclusions

Click or tap here to enter text. This study advances understanding of the multilevel determinants of PA among cancer survivors, highlighting that barriers and facilitators are interwoven across individual, social, and environmental contexts. Cancer survivors face substantial challenges during PA, including treatment-induced side effects, time limitations and fatigue. Limited patient education can lead to beliefs that PA is ineffective in reducing treatment-related side effects, such as fatigue. Enhanced support from healthcare providers may be needed to offer secure exercise suggestions for survivors to develop beneficial routines. Further research is required to assess the impact of educational strategies and provider interactions to overcome barriers and improve exercise compliance among cancer survivors.

Supplementary Materials

Appendix A: Socio-demographic questionnaire for Cancer survivors; Appendix B: Semi-structured questionnaire.

Author Contributions

Conceptualization: G.K.; Methodology, G.K.; Formal Analysis: G.K. and P.C.; Investigation, G.K.; Data Curation, G. K. Writing-Original Draft Preparation, G.K.; Writing-Review & Editing: G.K., P.C., A.G., J.K., L.S., and D.S.; Supervision, D. S. Project Administration, G.K.; Funding Acquisition, G.K.

Funding

This work was supported by the College of Public Health Sparks Student Research Award at the University of Nebraska Medical Center to Gaurav Kumar. The views, opinions, and arguments presented in this report do not necessarily reflect those of the funding agency.

Institutional Review Board Statement

The study was conducted in accordance with the Declaration of Helsinki and approved by the Institutional Review Board of the University of Nebraska Medical Center (protocol IRB# 0468-23-EX; approved on August 3, 2023).

Informed Consent Statement

Informed consent was obtained from all participants prior to each interview. No identifiable patient data were reported. Therefore, written informed consent for publication was not required for this study.

Data Availability Statement

The de-identified qualitative data supporting the findings of this study are available from the corresponding author, Gaurav Kumar (gaurav-kumar-3@ou.edu), upon reasonable request and are subject to Institutional Review Board restrictions on confidentiality.

Acknowledgments

The authors gratefully acknowledge the time and effort of the participating organizations in the recruitment process.
Competing Interests: The authors declare that they have no competing financial interests or personal relationships that could have influenced the work reported in this study.

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Table 1. Descriptive characteristics of the cancer survivors in the study (n=18).
Table 1. Descriptive characteristics of the cancer survivors in the study (n=18).
Characteristics N (%)
Age (years), mean± SD (range) 60.2 ± 11.4 (41-82)
Years sincediagnosis , mean ± SD (range) 8.6 ± 10.8 (1-42)
Gender
   Male
   Female

4 (22.2)
14 (77.8)
Race/Ethnicity
   Non-Hispanic White
   Non-Hispanic Black
   Hispanic
   Asian

9(50.0)
4 (22.2)
3 (16.7)
2 (11.1)
Marital Status
   Married/living with partner
   Divorced or single
   Widow/widower

14 (77.8)
3 (16.7)
1 (5.6)
Education Level
   Vocational school/Some college
   Associate
   Bachelor
   Masters
   Professional

7 (38.9)
3 (16.7)
2 (11.1)
1 (5.6)
5 (27.8)
Employment Status
   Employed full-time
   Employed part-time
   Retired
   Medical Leave
   Homemaker

6 (33.3)
2 (11.1)
8 (44.4)
1 (5.6)
1 (5.6)
Annual Income ($)
   <25,000
   25,000-<50,000
   50,000-<75,000
   ≥75,000

2 (11.1)
2 (11.1)
5 (27.8)
9 (50.0)
Insurance Type
   Medicare/Supplement
   Private

7 (38.9)
11(61.1)
Smoking Status
   Current
   Former
   Never

1 (5.6)
5 (27.8)
12 (66.7)
Alcohol consumption
   Current/Occasional
   Former
   Never

12 (66.6)
3 (16.7)
3 (16.7)
Co-morbidities
   Yes
   No

10 (55.5)
8 (44.5)
Cancer Diagnosis
   Breast
   Lung
   Colorectal
   Prostate
   Hodgkin Lymphoma (Hodgkin disease)
   Bone
   Kidney
   Vulvar
   Peritoneal Papillary serous

8 (44.4)
1 (5.5)
2 (11.1)
2 (11.1)
1 (5.5)
1 (5.5)
1 (5.5)
1 (5.5)
1 (5.5)
Cancer Stage
   I
   II
   III
   IV

1 (5.5)
5 (27.8)
9 (50.0)
3 (16.7)
Cancer Treatment
   Adjuvant chemotherapy
   Neoadjuvant chemotherapy
   Others*

7 (38.8)
6 (33.3)
5 (27.9)
*Others include (one each of Chemotherapy and Radiation, Hormone, Lumpectomy, Nephrectomy, Intravesical Therapy, Chemotherapy, and Stem cell transplant).
Table 2. Themes and subthemes related to physical activity among cancer survivors, mapped to the 12 domains of the Theoretical Domains Framework (TDF v1).
Table 2. Themes and subthemes related to physical activity among cancer survivors, mapped to the 12 domains of the Theoretical Domains Framework (TDF v1).
Themes Level Subthemes Aligned TDF v1 Domains
Barriers Individual Factors Lack of motivation and self-efficacy, limited awareness of PA guideline, time constraints, and physical constraints due to treatment effects and comorbidities. Knowledge; Motivation & Goals; Beliefs about Capabilities; Emotion; Memory, Attention & Decision Processes; Nature of Behavior
Social Factors Limited support from family, friends, and healthcare providers Social Influences; Social/Professional Role & Identity
Environmental Factors Limited resource accessibility and unfavorable weather. Environmental Context & Resources
Facilitators Individual Factors PA knowledge, PA motivation, PA Goals and health benefits. Knowledge; Motivation & Goals; Beliefs about Consequences; Behavioral Regulation; Nature of Behavior
Social Factors Support from family, friends, and healthcare providers Social Influences; Social/Professional Role & Identity; Emotion
Environmental Factors Weather and PA resources availability. Environmental Context & Resources
Recommendations Cancer Survivors Desire for more PA education and individualized programs; preference for enjoyable, flexible, and goal-oriented PA options Knowledge; Skills; Motivation & Goals; Behavioral Regulation
Oncology Care Providers Suggested improved PA counseling, resource sharing, and integration of exercise referrals into survivorship care plans Social/Professional Role & Identity; Environmental Context & Resources; Skills
Note: PA = physical activity; TDF = Theoretical Domains Framework (v1).
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