The accelerating integration of artificial intelligence (AI) into cybersecurity operations has introduced new challenges and opportunities for modernizing incident response (IR) practices. This study explores how cybersecurity practitioners perceive the adoption of intelligent automation and the readiness of legacy frameworks to address AI-driven threats. A structured, two-part quantitative survey was conducted among 194 U.S.-based professionals, capturing perceptions on operational effectiveness, trust in autonomous systems, and the adequacy of frameworks such as NIST and SANS. Using binary response formats and psychometric validation items, the study quantified views on AI’s role in reducing mean time to detect and respond, willingness to delegate actions to autonomous agents, and the perceived obsolescence of static playbooks. Findings indicate broad support for the modernization of incident response frameworks to better align with emerging AI capabilities and evolving operational demands. The results reveal a clear demand for modular, adaptive frameworks that integrate AI-specific risk models and decision auditability. These insights provide empirical grounding for the design of next-generation IR models and contribute to the strategic discourse on aligning automation capabilities with ethical, scalable, and operationally effective cybersecurity response.