Submitted:
25 November 2025
Posted:
25 November 2025
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Abstract

Keywords:
Introduction
0.0.0.1. Clinical and public health relevance.
Methods
Design and Data Source
Study Population and Inclusion Criteria
Anthropometry
Covariates and Subgroup Definitions
Survey Weighting and Variance Estimation
Complex Survey Design and Reproducibility
Primary Outcomes and Statistical Methods
Statistical Robustness and Precision Estimation
Clinical Outcome Analyses
Missing Data and Sensitivity Analyses
Data Quality Checks
NHANES 2021–2023 Sampling and Weighting Considerations
0.0.0.2. Analytic Inference Considerations
Post-Pandemic Weighting Considerations
Novelty & Justification for Posting
Results
Sample Characteristics
Overall BMI and Obesity Prevalence
Survey-Weighted BMI Distribution
Sex-Specific Results
Age-Stratified Prevalence
- 18–29 years: 28.52% (95% CI: 25.80%–31.35%)
- 30–39 years: 40.72% (95% CI: 37.40%–44.05%)
- 40–59 years: 46.07% (95% CI: 43.10%–49.05%)
- ≥60 years: 38.20% (95% CI: 35.10%–41.30%)
Race/Ethnicity
Adjusted Clinical Associations




| Characteristic | Unweighted n | Weighted estimate (%) or value |
|---|---|---|
| Total sample | 6,337 | — |
| Mean age, years | 47.7 | |
| Female | 3,479 | 51.3% |
| Male | 2,858 | 48.7% |
| Race/Ethnicity (weighted %) | ||
| Non-Hispanic White | 3,684 | 58.1% |
| Non-Hispanic Black | 791 | 12.5% |
| Hispanic | 1,095 | 18.1% |
| Non-Hispanic Asian | 353 | 5.6% |
| Other / Multiracial | 414 | 5.7% |
| Sex | Unweighted n | Mean BMI (kg/m2) | Obesity (%) |
|---|---|---|---|
| Male | 2,858 | 28.93 | 38.27% |
| Female | 3,479 | 29.35 | 40.15% |
| Age group | Unweighted n | Obesity (%) |
|---|---|---|
| 18–29 years | 927 | 28.52% |
| 30–39 years | 905 | 40.72% |
| 40–59 years | 1,733 | 46.07% |
| 60+ years | 2,772 | 38.20% |
| Race/Ethnicity | Unweighted n | Obesity (%) |
|---|---|---|
| Hispanic | 1,095 | 42.66% |
| Non-Hispanic White | 3,684 | 38.70% |
| Non-Hispanic Black | 791 | 49.22% |
| Non-Hispanic Asian | 353 | 13.32% |
| Other / Multiracial | 414 | 43.13% |
| Variable | aOR | 95% CI | p-value |
|---|---|---|---|
| Overweight (25.0–29.9 kg/m2) | 2.17 | 1.71–2.75 | 0.000371 |
| Obesity (≥30 kg/m2) | 5.58 | 4.31–7.22 | 0.00000361 |
| Age (per year) | 1.05 | 1.05–1.06 | 0.000000563 |
| Female sex (vs. male) | 0.78 | 0.65–0.93 | 0.0292 |
| Race/ethnicity (RIDRETH3) | 1.04 | 0.97–1.11 | 0.302 |
| Poverty-income ratio (INDFMPIR) | 0.85 | 0.78–0.92 | 0.00537 |
| Education level (DMDEDUC2) | 0.79 | 0.73–0.85 | 0.000339 |
| Health insurance (HIQ011) | 0.82 | 0.52–1.29 | 0.416 |
Sensitivity Analyses
Discussion
Principal Findings
0.0.0.3. Effect Size Interpretation
Interpretation of Effect Sizes
Rationale and Contribution of This Analysis
Context with Prior Evidence
Clinical and Public Health Implications
Clinical Relevance of Findings
Novel Contributions of This Study
Strengths and Limitations
0.0.0.4. Strengths
0.0.0.5. Limitations
What This Study Adds
- Provides the first nationally representative post-pandemic BMI and obesity estimates using the fully resumed NHANES 2021–2023 cycle.
- Quantifies demographic disparities with updated weighting that accounts for COVID-era sampling disruptions.
- Demonstrates clinically significant associations between BMI category and diabetes, highlighting population-level cardiometabolic risk.
Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Acknowledgments
Conflicts of Interest
References
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