Submitted:
09 May 2025
Posted:
09 May 2025
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Abstract
Keywords:
1. Introduction
2. Materials and Methods
3. Results.
3.1. Evolution of DME

3.2. Indications for DME
3.3. DME Technique
3.4. Microleakage & Marginal Adaptation
| Authors | Type of study | Bonding agent used | Means of evaluation | Results |
| Daghrery et al [34], 2024 | In vitro study | Total etch and 8th generation bonding agent | After thermal loading, marginal adaptation was assessed by measuring the vertical gaps between the lithium disilicate crown, the restorative material, and the underlying tooth structure. | Bulk fill flowable composite and bioactive composite demonstrated acceptable marginal adaptation. Glass ionomer cement produced the greatest change in vertical marginal adaptation. |
| Reddy et al [35], 2024 | In vitro study | Total etch and 5th generation bonding agent | Samples were examined for microleakage using confocal laser microscopy, and for interface integrity using scanning electron microscopy. | The use of glass ionomer cement (GIC) with hydroxyapatite addition ensures better marginal adaptation compared to flowable resins, but flowable resins create a more homogeneous surface. |
| Sadeghnezhad et al [1], 2024 | Meta-analysis | N/A | Data analysis was done by biostat software, 7 studies were included. | The use of DME had a positive effect in reducing microleakage compared to indirect restorations with subgingival extension. |
| Baldi et al [31], 2023 | In vitro study | Self-etch bonding agent | Specimens were scanned with micro-CT before after thermomechanical loading. | Flowable composites exhibited fewer interfacial gaps than nanohybrid composite. |
| Ismail HS et al [36], 2022 | Systematic review | N/A | Marginal adaptation was evaluated using a low vacuum scanning electron microscope. | Bulk-fill composites are recommended for proximal cavities with dentin/cementum margins, while RMGIs are better suited for poor moisture control or high caries risk. Despite bonding challenges, various adhesive protocols have shown comparable outcomes. |
| Vichitgomen et al [37], 2021 | In vitro study | 5th generation bonding agent | Marginal sealing ability at different interfaces was evaluated with a stereomicroscope at 40x magnification by scoring the depth of silver nitrate penetrating along the adhesive surfaces. | Microleakage was similar between DME and subgingival indirect restorations, but significantly higher with resin-modified glass ionomer cements. |
| Zhang et al [38], 2021 | In vitro study | Total etch | Specimens were coated with two layers of nail varnish extending 1 mm beyond the crown margins and immersed in a 0.55% methylene blue solution. Gingival microleakage was then evaluated under a stereomicroscope. | In endodontically treated teeth restored with an endocrown extending into the pulpal chamber, DME increased fracture resistance but did not reduce microleakage levels. |
| Jawaed et al [32], 2016 | In vitro study | Total etch | Specimens were sealed with acid-resistant varnish, leaving a 1 mm margin around the cervical area, and immersed in 2% buffered methylene blue solution for 24 hours. Microleakage was evaluated under a stereomicroscope, scored (0–4), and measured in millimeters. | The "snowplow" technique ensures lower microleakage in DME situations, because it reduces the thickness of the flowable resin at the base, which—due to its lower filler content—exhibits greater polymerization shrinkage. |
| Spreafico et al [21], 2016 | In vitro study | 4th generation bonding agent | Gold-sputtered epoxy replicas mounted on aluminum stubs were examined under SEM at 50X magnification. | No statistically significant differences in microleakage levels were found between margins with and without DME for indirect restorations. |
| Frankenberger et al [39], 2012 | In vitro study | Self-adhesive resin cements; | Microgaps were analyzed with SEM Analysis. | Direct bonding of glass ceramics to dentin showed the fewest microgaps (92%), followed by bonding to three-layered composite resin (84%), while repositioning with self-curing resin cement resulted in significantly more microgaps. |
| Stockton et al [33], 2007 | In vitro study | 5 groups: total etch; 6th generation; 7th generation; resin-modified-glass-ionomer-cement | Marginal integrity was measured by the percentage of surface area stained by silver nitrate solution. | On dentin, self-etch systems yielded lower microleakage rates. On enamel, they showed increased rates. |
3.5. Bond Strength & Layering
| Authors | Type of study | Bonding agent used | Means of evaluation | Results |
| Ismail et al [42], 2024 | In vitro study | 7th & 8th generation bonding agents | Specimens underwent μTBS testing after aging. | Light-cured adhesives showed the weakest μTBS to root-proximal dentin, while chemical and dual-cured agents performed comparably. |
| Balci et al [40], 2024 | In vitro study | Bonding agent N/A. Materials used for elevation: flowable composite, condensable composite. |
Static force was applied at an angle of 15° to the point of fracture. Fracture strength was measured and fracture types were examined under x6 magnification. | Flowable and condensable composite resin exhibited similar fracture resistance. |
| Juloski et al [43], 2020 | In vitro study | 7th generation bonding agent | SEM evaluation of marginal adaptation & microleakage evaluation with nail varnish | Self-etching or universal adhesives are recommended for DME to prevent dentin over-etching. |
| de Mattos Pimenta Vidal et al [44], 2012 | In vitro study | 5th generation b.a.; resin-modified-glass-ionomer | Two slabs per tooth were used for μTBS testing and two for nanoleakage assessment, based on penetration length (%) and silver nitrate deposition. | The presence of flowable composite significantly decreased micro tensile bond strength after aging simulation. |
3.6. Periodontal Response
3.7. Failure Rate
4. Discussion
4.1. Material Selection for DME
4.2. Long-Term Performance of DME
4.3. Relationship Between DME and Periodontal Health
4.4. Alternative Techniques for Managing Subgingival Cervical Margins
4.5. Decision-Making and New Classifications
4.6. Clinical Considerations
4.7. Strengths and Limitations
5. Conclusions
Author Contributions
Funding
Data Availability Statement
Acknowledgments
Conflicts of Interest
Abbreviations
| DME | Deep Margin Elevation |
| STA | Supracrestal Tissue Attachment |
| IDS | Immediate Dentin Sealing |
| PTFE | Polytetrafluoroethylene |
| GIC | Glass Ionomer Cement |
| μTBS | Micro Tensile Bond Strength |
| BoP | Bleeding on Probing |
| PI | Plaque Index |
| PPD | Probing Pocket Depth |
| GI | Gingival Index |
| SCL | Surgical Crown Lengthening |
| RMGIC | Resin Modified Glass Ionomer |
| OE | Orthodontic Extrusion |
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| Authors | Type of study | Means of evaluation | Results |
| Hausdörfer et al [45], 2024 | Prospective controlled clinical trial | Following DME combined with indirect restoration, periodontal response was assessed with BoP, PI, PPD with a follow-up of 1 year | Proximal boxes treated with DME were correlated with increased risk of gingival inflammation. |
| Felemban et al [5], 2023 | Systematic review | 68 articles were included | If the cervical margin is <2 mm from the bone crest, DME is contraindicated, and surgical crown lengthening (SCL) should be performed. |
| Ghezzi et al [46], 2019 | Case series | Periodontal response was assessed with BoP | When the supracrestal tissue attachment (STA) is respected (>2.04 mm from the bone crest), DME is compatible with periodontal health, with reduced bleeding on probing observed over 12 months. |
| Bertoldi et al [47], 2019 | Clinical study | Periodontal response was assessed with full-mouth plaque and bleeding score, focal probing depth. | The DME technique is compatible with periodontal health, at levels similar to intact tooth surfaces. |
| Ferrari et al [25], 2017 | Clinical study | Periodontal response was assessed with BoP, GI, and PI. | A flat contour of the intermediate layer after deep margin elevation (DME) has been associated with intense inflammatory infiltration and subsequent bone resorption, while clinical observations reported an increased incidence of bleeding on probing around DME-treated surfaces; however, although elevated bleeding on probing was also noted at 12 months post-treatment, no bone resorption was detected, likely due to the insufficient follow-up period. |
| Oppermann et al [48] | Clinical study | Periodontal response was assessed with BoP, GI, and PI. | It was observed that subgingivally placed restorations had comparable behavior to sites treated with crown lengthening. |
| Padbury et al [49], 2003 | Literature review | Periodontal response was assessed with BoP and probing depth. | Overextended material near soft tissues can severely compromise periodontal health. |
| Authors | Type of study | Type of failure | Results |
| Adson et al [56], 2024 | Retrospective clinical stydy | Failures included marginal integrity (n=1) | Out of 50 indirect partial restorations with DME, the 6-months survival rate was 98%. |
| Gözetici-Çil et al [57], 2024 | Retrospective clinical study | Failures included: partial loss (n=5), material chipping (n=4), secondary caries (n=1) | Out of 80 indirect partial composite restorations with DME, the 3-year survival rate was 93.8%. |
| Aziz et al [58], 2024 | Retrospective clinical study | Failures included: secondary caries (n=15), pulpal necrosis (n=4), crown fractures (n=4), loss of crown retention (n=3) | Out of 153 restorations with DME and CAD/CAM crowns, the 10-year survival rate was 95.8%, with no significant differences between groups with or without DME. |
| Muscholl et al [59], 2022 |
Retrospective clinical study | No failures were recorded. Periodontal parameters assessed included bleeding on probing, gingival bleeding index, and plaque control record. | Out of the 60 participants included, no failures were recorded in a follow-up range of 2.70 ± 1.90 years. |
| Bresser et al [50], 2019 | Retrospective clinical study | Failures included: secondary caries (n=5), pulpal necrosis (n=1), severe periodontal breakdown (n=1) and fracture (n=1) | Out of the 197 restorations with DME included, 8 failures occurred between 46-57 months. |
| Kuper et al [53], 2011 | Retrospective clinical study | Failures included: secondary caries (n=44), fracture tooth (n=6), fracture restoration (n=8), extraction (n=10), other/unknown (n=4) | Out of 344 composite restorations with margins apical to the CEJ, 72 failures were recorded, with no details provided on material selection or layering technique. |
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