Submitted:
02 May 2025
Posted:
06 May 2025
You are already at the latest version
Abstract
Keywords:
1. Introduction
2. The Rise and Plateau of Sustainability Discourse
3. The Technological Takeover: AI, Robotics, and Automation
4. The Crisis of Relevance: Where Does Green Chemistry Stand Now?
5. Toward a New Sustainability: Data-Driven, Embedded, Unpreached
6. Opportunities for Chemists and Scientists in the New Age
7. Conclusion
Conflicts of Interest
Abbreviations
| AI | Artificial Intelligence |
| CSR | Corporate Social Responsibility |
| ESG | Environmental, Social, and Governance |
| GRI | Global Reporting Initiative |
| LCA | Lifecycle Assessment |
| ML | Machine Learning |
| QSAR | Quantitative Structure-Activity Relationship |
| RPA | Robotic Process Automation |
References
- ElAlfy, A.; Palaschuk, N.; El-Bassiouny, D.; Wilson, J.; Weber, O. Scoping the Evolution of Corporate Social Responsibility (CSR) Research in the Sustainable Development Goals (SDGs) Era. Sustainability 2020, 12, 5544. [Google Scholar] [CrossRef]
- Anastas, P.T.; Warner, J.C. Green Chemistry: Theory and Practice. Green Chem. [CrossRef]
- Patrício, L.; Varela, L.; Silveira, Z. Integration of Artificial Intelligence and Robotic Process Automation: Literature Review and Proposal for a Sustainable Model. Appl. Sci. 2024, 14, 9648. [Google Scholar] [CrossRef]
- Brundtland, G.H. (1987) Our Common Future Report of the World Commission on Environment and Development. Geneva, UN-Dokument A/42/427.
- Rockström, J.; Steffen, W.; Noone, K.; Persson, Å.; Chapin, F.S.; Lambin, E.F.; et al. A Safe Operating Space for Humanity. Nature 2009, 461, 472–475. [Google Scholar] [CrossRef] [PubMed]
- Geels, F.W. Socio-Technical Transitions to Sustainability: A Review of Criticisms and Elaborations of the Multi-Level Perspective. Curr. Opin. Environ. Sustain. 2019, 39, 187–201. [Google Scholar] [CrossRef]
- ElAlfy, A.; Palaschuk, N.; El-Bassiouny, D.; Wilson, J.; Weber, O. Scoping the Evolution of Corporate Social Responsibility (CSR) Research in the Sustainable Development Goals (SDGs) Era. Sustainability 2020, 12, 5544. [Google Scholar] [CrossRef]
- P.T. Anastas and J.C. Warner, in Green Chemistry: Theory and Practice, Oxford University Press, New York, 1998; I. Horvath and P. T. Anastas, Chem. Rev. 2007, 107, 2167.
- Lam, E.; Moores, A.; Subramaniam, B.; Voutchkova-Kostal, A. Defining and Advancing Sustainable Chemistry: A Discussion around the Recent National Science and Technology Council Report. ACS Sustainable Chemistry & Engineering 2023, 11, 17881–17884. [Google Scholar] [CrossRef]
- Esty, D.C. The sustainability imperative. SSRN Electronic Journal 2021. [Google Scholar] [CrossRef]
- Manninen, K.; Huiskonen, J. Factors influencing the implementation of an integrated corporate sustainability and business strategy. Journal of Cleaner Production 2022, 343, 131036. [Google Scholar] [CrossRef]
- Sheldon, R.A. The E factor 25 years on: the rise of green chemistry and sustainability. Green Chemistry 2016, 19, 18–43. [Google Scholar] [CrossRef]
- Delmas, M.A.; Burbano, V.C. The drivers of greenwashing. California Management Review 2011, 54, 64–87. [Google Scholar] [CrossRef]
- Müller, J.M.; Kiel, D.; Voigt, K.-I. What Drives the Implementation of Industry 4.0? The Role of Opportunities and Challenges in the Context of Sustainability. Sustainability 2018, 10, 247. [Google Scholar] [CrossRef]
- Adewale, B.A.; Ene, V.O.; Ogunbayo, B.F.; Aigbavboa, C.O. A Systematic Review of the Applications of AI in a Sustainable Building's Lifecycle. Buildings 2024, 14, 2137. [Google Scholar] [CrossRef]
- Ananikov, V.P. Top 20 influential AI-based technologies in chemistry. Artificial Intelligence Chemistry 2024, 2, 100075. [Google Scholar] [CrossRef]
- Patrício, L.; Varela, L.; Silveira, Z. Integration of Artificial Intelligence and Robotic Process Automation: Literature Review and Proposal for a Sustainable Model. Appl. Sci. 2024, 14, 9648. [Google Scholar] [CrossRef]
- Bonilla, S.H.; Silva, H.R.O.; Terra da Silva, M.; Franco Gonçalves, R.; Sacomano, J.B. Industry 4.0 and Sustainability Implications: A Scenario-Based Analysis of the Impacts and Challenges. Sustainability 2018, 10, 3740. [Google Scholar] [CrossRef]
- Wu, D.; Rosen, D.W.; Wang, L.; Schaefer, D. Cloud-based design and manufacturing: A new paradigm in digital manufacturing and design innovation. Computer-Aided Design 2014, 59, 1–14. [Google Scholar] [CrossRef]
- Nahavandi, S. Industry 5.0—A Human-Centric Solution. Sustainability 2019, 11, 4371. [Google Scholar] [CrossRef]
- Agrawal, A.; Gans, J.; Goldfarb, A. (2022). Prediction machines, updated and expanded: The Simple Economics of Artificial Intelligence.
- Venkatasubramanian, V. The promise of artificial intelligence in chemical engineering: Is it here, finally? AIChE Journal 2018, 65, 466–478. [Google Scholar] [CrossRef]
- Moses, O.A.; Chen, W.; Adam, M.L.; Wang, Z.; Liu, K.; Shao, J.; Li, Z.; Li, W.; Wang, C.; Zhao, H.; Pang, C.H.; Yin, Z.; Yu, X. Integration of data-intensive, machine learning and robotic experimental approaches for accelerated discovery of catalysts in renewable energy-related reactions. Materials Reports Energy 2021, 1, 100049. [Google Scholar] [CrossRef]
- Hassoun, A.; Prieto, M.A.; Carpena, M.; Bouzembrak, Y.; Marvin, H.J.; Pallarés, N.; Barba, F.J.; Bangar, S.P.; Chaudhary, V.; Ibrahim, S.; Bono, G. Exploring the role of green and Industry 4.0 technologies in achieving sustainable development goals in food sectors. Food Research International 2022, 162, 112068. [Google Scholar] [CrossRef]
- Ley, S.V.; Fitzpatrick, D.E.; Ingham, R.J.; Myers, R.M. Organic Synthesis: March of the Machines. Angewandte Chemie International Edition, 2015, 54, 3449–3464. [Google Scholar] [CrossRef]
- Cumming, D.; Saurabh, K.; Rani, N.; Upadhyay, P. Towards AI ethics-led sustainability frameworks and toolkits: Review and research agenda. Journal of Sustainable Finance and Accounting 2024, 1, 100003. [Google Scholar] [CrossRef]
- Zimmerman, J.B.; Anastas, P.T.; Erythropel, H.C.; Leitner, W. Designing for a green chemistry future. Science 2020, 367, 397–400. [Google Scholar] [CrossRef] [PubMed]
- Rietdorf, C.; Torolsan, K.; Favier, M.; Krishna, S.; Henke, A.; Wahl, K.; Oberle, M.; Defranceski, M.; Koch, D.; Schwarz, J.; Miehe, R. Leveraging digital twins for Real-Time environmental monitoring in battery manufacturing. Procedia CIRP 2024, 130, 749–754. [Google Scholar] [CrossRef]
- Roberts, H.; Zhang, J.; Bariach, B.; Cowls, J.; Gilburt, B.; Juneja, P.; Tsamados, A.; Ziosi, M.; Taddeo, M.; Floridi, L. Artificial intelligence in support of the circular economy: ethical considerations and a path forward. AI & Society 2022, 39, 1451–1464. [Google Scholar] [CrossRef]
- Ha, T.; Lee, D.; Kwon, Y.; Park, M.S.; Lee, S.; Jang, J.; Choi, B.; Jeon, H.; Kim, J.; Choi, H.; Seo, H.; Choi, W.; Hong, W.; Park, Y.J.; Jang, J.; Cho, J.; Kim, B.; Kwon, H.; Kim, G.; Choi, Y. AI-driven robotic chemist for autonomous synthesis of organic molecules. Science Advances 2023, 9. [Google Scholar] [CrossRef] [PubMed]
- Shaddick, G.; Topping, D.; Hales, T.C.; Kadri, U.; Patterson, J.; Pickett, J.; Petri, I.; Taylor, S.; Li, P.; Sharma, A.; et al. Data Science and AI for Sustainable Futures: Opportunities and Challenges. Sustainability 2025, 17, 2019. [Google Scholar] [CrossRef]
- Cavasotto, C.N.; Scardino, V. Machine Learning Toxicity Prediction: Latest advances by Toxicity End Point. ACS Omega 2022, 7, 47536–47546. [Google Scholar] [CrossRef]
- Weber, J.M.; Guo, Z.; Zhang, C.; Schweidtmann, A.M.; Lapkin, A.A. Chemical data intelligence for sustainable chemistry. Chemical Society Reviews 2021, 50, 12013–12036. [Google Scholar] [CrossRef]
- Mace, S.; Xu, Y.; Nguyen, B.N. Automated Transition Metal Catalysts Discovery and Optimisation with AI and Machine Learning. ChemCatChem 2024, 16. [Google Scholar] [CrossRef]
Disclaimer/Publisher’s Note: The statements, opinions and data contained in all publications are solely those of the individual author(s) and contributor(s) and not of MDPI and/or the editor(s). MDPI and/or the editor(s) disclaim responsibility for any injury to people or property resulting from any ideas, methods, instructions or products referred to in the content. |
© 2025 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).