Preprint Article Version 1 Preserved in Portico This version is not peer-reviewed

Antifungal Effects of the Fermented Sophora flavescens and Eleutherococcus sessiliflorus Extract

Version 1 : Received: 17 April 2024 / Approved: 18 April 2024 / Online: 18 April 2024 (14:01:57 CEST)

How to cite: Kim, J.Y.; Chae, M.J.; Son, Y.G.; Jo, S.M.; Kang, N.R.; Kang, S.D.; Kim, K.D.; Lee, S.W.; Kim, J.Y. Antifungal Effects of the Fermented Sophora flavescens and Eleutherococcus sessiliflorus Extract. Preprints 2024, 2024041248. https://doi.org/10.20944/preprints202404.1248.v1 Kim, J.Y.; Chae, M.J.; Son, Y.G.; Jo, S.M.; Kang, N.R.; Kang, S.D.; Kim, K.D.; Lee, S.W.; Kim, J.Y. Antifungal Effects of the Fermented Sophora flavescens and Eleutherococcus sessiliflorus Extract. Preprints 2024, 2024041248. https://doi.org/10.20944/preprints202404.1248.v1

Abstract

In this study, the microbial strain was isolated from the humus soil to ferment Sophora flavescens and Eleutherococcus sessiliflorus extracts. The isolated microbial was identified as Bacillus genus by 16S rRNA sequence analysis. The fermented plant extracts exhibited the antifungal effects against four types of the plant pathogens such as P. carotorum, B. cinerea, C. fructicola Sau-3, and C. gloeosporioides according to incubation time. Especially, the fermented plant extracts showed the most active activities for Colletotrichum genus to inhibit mycelium growth. Metabolite changes in fermented S. flavescens and E. sessiliflorus extracts were confirmed through LC-Q-TOF/MS. Flavonoid and peptide derivatives were improved in fermented S. flavescens and E. sessiliflorus extracts compared to their unfermented one, respectively. This study suggested that the isolated Bacillus microbial fermentation could be a valuable tool in improving the bioactivity of S. flavescens and E. sessiliflorus extracts to have potential with more environmentally-friendly antifungal agents.

Keywords

Antifungal effects; Sophora flavescens; Elutherococcus sessiliflorus; Fermented plant exract; LC-Q-TOF/MS analysis

Subject

Biology and Life Sciences, Biology and Biotechnology

Comments (0)

We encourage comments and feedback from a broad range of readers. See criteria for comments and our Diversity statement.

Leave a public comment
Send a private comment to the author(s)
* All users must log in before leaving a comment
Views 0
Downloads 0
Comments 0
Metrics 0


×
Alerts
Notify me about updates to this article or when a peer-reviewed version is published.
We use cookies on our website to ensure you get the best experience.
Read more about our cookies here.