Preprint Review Version 1 Preserved in Portico This version is not peer-reviewed

Polyphenols of the Inuleae-Inulinae and Their Biological Activities: A Review

Version 1 : Received: 3 April 2024 / Approved: 3 April 2024 / Online: 4 April 2024 (17:34:30 CEST)

A peer-reviewed article of this Preprint also exists.

Malarz, J.; Michalska, K.; Stojakowska, A. Polyphenols of the Inuleae-Inulinae and Their Biological Activities: A Review. Molecules 2024, 29, 2014. Malarz, J.; Michalska, K.; Stojakowska, A. Polyphenols of the Inuleae-Inulinae and Their Biological Activities: A Review. Molecules 2024, 29, 2014.

Abstract

Polyphenols are ubiquitous plant metabolites that demonstrate biological activities essential to the plant-environment interactions. They are of interest to plant food consumers, as well as to the food, pharmaceutical and cosmetic industry. The class of the plant metabolites comprises both widespread (chlorogenic acids, luteolin, quercetin) and unique compounds of diverse chemical structures but of the common biosynthetic origin. Polyphenols, next to sesquiterpenoids are regarded as the major class of the Inuleae-Inulinae metabolites responsible for the pharmacological activity of medicinal plants from the subtribe (Blumea spp., Dittrichia spp., Inula spp., Pulicaria spp. and others). Recent decades have brought a rapid development of molecular and analytical techniques which resulted in better understanding of the taxonomic relationships within the Inuleae tribe and in a plethora of data concerning the chemical constituents of the Inuleae-Inulinae. The current taxonomical classification has introduced changes in the well-established botanical names and rearranged the genera based on molecular plant genetic studies. The newly created chemical data together with the earlier phytochemical studies may provide some complementary information on biochemical relationships within the subtribe. Moreover, they may at least partly explain pharmacological activities of the plant preparations traditionally used in therapy. The current review aimed to systematize the knowledge on the polyphenols of the Inulae-Inulinae.

Keywords

Blumea; chalcone; coumarin; Dittrichia; flavone; flavonol; hydroxycinnamate; Inula; lignan; Pulicaria

Subject

Biology and Life Sciences, Plant Sciences

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