Preprint Article Version 2 Preserved in Portico This version is not peer-reviewed

Evaluation of the Effect of Primary and Secondary Closure on the Use of Leukocyte and Platelet Rich Fibrin in Impacted Lower Third Molar Surgery

Version 1 : Received: 1 April 2024 / Approved: 1 April 2024 / Online: 1 April 2024 (14:42:33 CEST)
Version 2 : Received: 18 April 2024 / Approved: 18 April 2024 / Online: 19 April 2024 (11:27:49 CEST)

How to cite: ORHAN, Z.D.; CİĞERİM, L.; GÜZEL, M.; DOĞRU, İ.; ALSMADI, M.; KAHRAMAN, N.H.; HUSSEİN, A. Evaluation of the Effect of Primary and Secondary Closure on the Use of Leukocyte and Platelet Rich Fibrin in Impacted Lower Third Molar Surgery. Preprints 2024, 2024040094. https://doi.org/10.20944/preprints202404.0094.v2 ORHAN, Z.D.; CİĞERİM, L.; GÜZEL, M.; DOĞRU, İ.; ALSMADI, M.; KAHRAMAN, N.H.; HUSSEİN, A. Evaluation of the Effect of Primary and Secondary Closure on the Use of Leukocyte and Platelet Rich Fibrin in Impacted Lower Third Molar Surgery. Preprints 2024, 2024040094. https://doi.org/10.20944/preprints202404.0094.v2

Abstract

The aim of this study was to compare the effect of using L-PRF in patients undergoing impacted lower third molar surgery with either primary or secondary closure techniques. Methods: This prospective, randomised, double-blind, split-mouth clinical trial was conducted in patients with bilateral lower impacted third molars of similar position. Primary closure was performed in group 1 and secondary closure in group 2. Group 1 closure technique was applied to one side of the patients and group 2 closure technique was applied to the other side at different times. Nine pa-tients were excluded from the study due to alveolitis and failure to attend regular control visits out of the 45 patients evaluated. Results: Of the 36 patients included in the study, 23 were female and 13 were male and the mean age was 22.42±3.36 years. The secondary closure group had lower VAS scores at hour 6 (p

Keywords

leukocyte and platelet rich fibrin; closure techniques; wound healing; regenerative medicine; primary closure; secondary closure; impacted third molar

Subject

Medicine and Pharmacology, Dentistry and Oral Surgery

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