Version 1
: Received: 1 April 2024 / Approved: 1 April 2024 / Online: 1 April 2024 (14:41:38 CEST)
How to cite:
Yang, C.; Yu, Y.; An, J. Effect of High Sucrose Diet on the Occurrence and Progression of Diabetic Retinopathy and Dietary Modification Strategies. Preprints2024, 2024040085. https://doi.org/10.20944/preprints202404.0085.v1
Yang, C.; Yu, Y.; An, J. Effect of High Sucrose Diet on the Occurrence and Progression of Diabetic Retinopathy and Dietary Modification Strategies. Preprints 2024, 2024040085. https://doi.org/10.20944/preprints202404.0085.v1
Yang, C.; Yu, Y.; An, J. Effect of High Sucrose Diet on the Occurrence and Progression of Diabetic Retinopathy and Dietary Modification Strategies. Preprints2024, 2024040085. https://doi.org/10.20944/preprints202404.0085.v1
APA Style
Yang, C., Yu, Y., & An, J. (2024). Effect of High Sucrose Diet on the Occurrence and Progression of Diabetic Retinopathy and Dietary Modification Strategies. Preprints. https://doi.org/10.20944/preprints202404.0085.v1
Chicago/Turabian Style
Yang, C., Yifei Yu and Jianhong An. 2024 "Effect of High Sucrose Diet on the Occurrence and Progression of Diabetic Retinopathy and Dietary Modification Strategies" Preprints. https://doi.org/10.20944/preprints202404.0085.v1
Abstract
As the most serious of the many worse new pathological changes caused by diabetes, there are many risk factors for the occurrence and development of DR. It mainly includes hyperglycemia, hypertension, hyperlipidemia and so on. Among them, hyperglycemia is the most critical cause, which plays a key role in the pathological changes of DR.High-sucrose diets(HSDs) lead to elevated blood glucose levels in vivo, which, through oxidative stress, inflammation, the production of AGEs and VEGF, causes plenty of pathological damages to the retina and ultimately bring about loss of vision. The existing therapies for DR primarily target the terminal stage of the disease, when irreversible visual impairment has appeared. Therefore, early prevention is particularly critical. Early prevention of DR-related vision loss requires adjustments to dietary habits, mainly by reducing sugar intake. This article primarily discusses the risk factors, pathophysiological processes, and molecular mechanisms associated with the development of DR caused by HSDs. It aims to raise awareness of the crucial role of diet in the occurrence and progression of DR, promote timely changes in dietary habits, prevent vision loss, and improve the quality of life. The aim is to make people aware of the importance of diet in the occurrence and progression of DR. According to the dietary modification strategies we give, patients can change their poor eating habits timely, avoid the retinopathy that can be avoided theoretically, and obtain a excellent outcome.
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
