Preprint Review Version 1 Preserved in Portico This version is not peer-reviewed

Nuclear Phospholipids and Signaling: An Update of the Story

Version 1 : Received: 27 March 2024 / Approved: 28 March 2024 / Online: 28 March 2024 (14:29:15 CET)

A peer-reviewed article of this Preprint also exists.

Casalin, I.; Ceneri, E.; Ratti, S.; Manzoli, L.; Cocco, L.; Follo, M.Y. Nuclear Phospholipids and Signaling: An Update of the Story. Cells 2024, 13, 713. Casalin, I.; Ceneri, E.; Ratti, S.; Manzoli, L.; Cocco, L.; Follo, M.Y. Nuclear Phospholipids and Signaling: An Update of the Story. Cells 2024, 13, 713.

Abstract

In the last three decades the presence of phospholipids in the nucleus has been shown and thoroughly investigated. A great interest raised about nuclear inositol lipids mainly because of their role in signalling acting. Here we review the main issues of nuclear phospholipid localization and the role of nuclear inositol lipids and their related enzymes in cellular signaling both in physiological and pathological conditions.

Keywords

nucleus; phosphoinositides; pholipases C; myelodysplastic neoplasm (MDS); muscle; brain

Subject

Biology and Life Sciences, Life Sciences

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