Preprint Review Version 1 Preserved in Portico This version is not peer-reviewed

Toxic Effects of Rare Earth Elements on Human Health

Version 1 : Received: 11 March 2024 / Approved: 11 March 2024 / Online: 12 March 2024 (04:29:15 CET)

A peer-reviewed article of this Preprint also exists.

Wang, W.; Yang, Y.; Wang, D.; Huang, L. Toxic Effects of Rare Earth Elements on Human Health: A Review. Toxics 2024, 12, 317. Wang, W.; Yang, Y.; Wang, D.; Huang, L. Toxic Effects of Rare Earth Elements on Human Health: A Review. Toxics 2024, 12, 317.

Abstract

Rare earth elements (REEs) are a type of new material resources, which have attracted significant attention in recent years. REEs have emerged as essential metals in modern-day technology due to their unique functions. Long-term large-scale mining and utilization of rare earths have caused serious environmental pollution and constitutes a global health issue, which raised concerns about human health safety. However, the toxicity profile of suspended particulate matter of REEs in the environment interacts with the human body in remain largely unknown. Studies have shown that REEs can enter the human body through a variety of pathways, leading to a variety of organ and system dysfunctions through changes in genetics, epigenetics, and signaling pathways. Through an extensive literature search and critical analysis, we provide a comprehensive overview of the available evidence, identify knowledge gaps, and make recommendations for future research directions.

Keywords

Rare earth element; Human health; Toxicity effect; Toxicity mechanism

Subject

Public Health and Healthcare, Public, Environmental and Occupational Health

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