Preprint Article Version 1 Preserved in Portico This version is not peer-reviewed

Systemic Inflammation Index: A New Candidate Minor Criterion in the Diagnosis of Polycythemia vera

Version 1 : Received: 7 March 2024 / Approved: 7 March 2024 / Online: 7 March 2024 (12:04:07 CET)

How to cite: Gulturk, E.; Kapucu, K. Systemic Inflammation Index: A New Candidate Minor Criterion in the Diagnosis of Polycythemia vera. Preprints 2024, 2024030449. https://doi.org/10.20944/preprints202403.0449.v1 Gulturk, E.; Kapucu, K. Systemic Inflammation Index: A New Candidate Minor Criterion in the Diagnosis of Polycythemia vera. Preprints 2024, 2024030449. https://doi.org/10.20944/preprints202403.0449.v1

Abstract

Aim: To investigate inflammation indices and erythropoietin (EPO) levels for their potential role in distinguishing polycythemia vera (PV) from secondary polycythemia (SP), and to compare different parameter combinations in terms of diagnostic accuracy. Methods: This retrospective cohort was created from patients assessed for polycythemia from January 2020 to December 2023. PV diagnosis was made according to the 2016 WHO criteria (n=145). Those who did not fulfill the criteria were defined as having SP (n=84). Results: NLR, PLR and SII were significantly higher in the PV group (p

Keywords

polycythemia vera; secondary polycythemia; systemic inflammation index; erythropoietin; neutrophil-to-lymphocyte ratio; platelet-to-lymphocyte ratio

Subject

Medicine and Pharmacology, Hematology

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