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Enhancement of Classifier Performance with Adam and RanAdam Hyper Parameter Tuning for Lung Cancer detection from Microarray Data - In Pursuit of Precision
M S, K.; Rajaguru, H.; Nair, A.R. Enhancement of Classifier Performance with Adam and RanAdam Hyper-Parameter Tuning for Lung Cancer Detection from Microarray Data—In Pursuit of Precision. Bioengineering2024, 11, 314.
M S, K.; Rajaguru, H.; Nair, A.R. Enhancement of Classifier Performance with Adam and RanAdam Hyper-Parameter Tuning for Lung Cancer Detection from Microarray Data—In Pursuit of Precision. Bioengineering 2024, 11, 314.
M S, K.; Rajaguru, H.; Nair, A.R. Enhancement of Classifier Performance with Adam and RanAdam Hyper-Parameter Tuning for Lung Cancer Detection from Microarray Data—In Pursuit of Precision. Bioengineering2024, 11, 314.
M S, K.; Rajaguru, H.; Nair, A.R. Enhancement of Classifier Performance with Adam and RanAdam Hyper-Parameter Tuning for Lung Cancer Detection from Microarray Data—In Pursuit of Precision. Bioengineering 2024, 11, 314.
Abstract
Microarray gene expression analysis is a powerful technique used in cancer classification and research to identify and understand gene expression patterns that can differentiate between different cancer types, subtypes, and stages. However, microarray databases are highly redundant, inherently nonlinear, and noisy. Therefore, extracting meaningful information from such a huge database is a challenging one. The paper adopts the Fast Fourier Transform (FFT) and Mixture Model (MM) for dimensionality reduction and utilizes the Dragonfly optimization algorithm as the feature selection technique. The classifiers employed in this research are Nonlinear Regression, Naïve Bayes, Decision Tree, Random Forest and SVM (RBF). The classifiers' performances are analyzed with and without feature selection methods. Finally, Adaptive Moment Estimation (Adam) and Random Adaptive Moment Estimation (RanAdam) hyper-parameter tuning techniques are used as improvisation techniques for classifiers. The SVM (RBF) classifier with the Fast Fourier Transform Dimensionality Reduction method and Dragonfly feature selection achieved the highest accuracy of 98.343% with RanAdam hyperparameter tuning compared to other classifiers.
Keywords
Lung cancer detection; MAGE data; DimRe; Cancer classification; Adam and RanAdam tuning; FFT; Mixture Model
Subject
Engineering, Bioengineering
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
