Preprint Article Version 1 Preserved in Portico This version is not peer-reviewed

Comparison of Double Casting Methods for Microfluidic Device Fabrication

Version 1 : Received: 23 February 2024 / Approved: 26 February 2024 / Online: 26 February 2024 (11:42:36 CET)

How to cite: Cherry, B.; Orcutt, A.; Tompkins, N. Comparison of Double Casting Methods for Microfluidic Device Fabrication. Preprints 2024, 2024021437. https://doi.org/10.20944/preprints202402.1437.v1 Cherry, B.; Orcutt, A.; Tompkins, N. Comparison of Double Casting Methods for Microfluidic Device Fabrication. Preprints 2024, 2024021437. https://doi.org/10.20944/preprints202402.1437.v1

Abstract

We compare two methods for creating a microfluidic device from an initial positive master with the same surface relief as the final device. The first method uses urethane or epoxy resin to create an intermediate master for PDMS casting. This method has a very low failure rate but a longer processing time. The second method utilizes PDMS double casting where the intermediate master is passivated PDMS. This method has a higher failure rate but a significantly shorter processing time. Detailed methodology for both methods is included along with a comparison of the strengths and weaknesses of each method. The resin intermediate is a simpler method while PDMS double casting is faster and more scalable. Ultimately it is found that PDMS double casting is preferable in most situations.

Keywords

microfluidics; soft lithography; double casting; PDMS

Subject

Chemistry and Materials Science, Materials Science and Technology

Comments (0)

We encourage comments and feedback from a broad range of readers. See criteria for comments and our Diversity statement.

Leave a public comment
Send a private comment to the author(s)
* All users must log in before leaving a comment
Views 0
Downloads 0
Comments 0
Metrics 0


×
Alerts
Notify me about updates to this article or when a peer-reviewed version is published.
We use cookies on our website to ensure you get the best experience.
Read more about our cookies here.