Preprint Review Version 1 Preserved in Portico This version is not peer-reviewed

Progress in the Application of 3D Skin Models for Cosmetic Assessment

Version 1 : Received: 22 February 2024 / Approved: 23 February 2024 / Online: 23 February 2024 (09:22:25 CET)

How to cite: Shuxian, C.; Qin, W.; Yunlian, D.; Shenjia, L.; Ruilian, Y. Progress in the Application of 3D Skin Models for Cosmetic Assessment. Preprints 2024, 2024021340. https://doi.org/10.20944/preprints202402.1340.v1 Shuxian, C.; Qin, W.; Yunlian, D.; Shenjia, L.; Ruilian, Y. Progress in the Application of 3D Skin Models for Cosmetic Assessment. Preprints 2024, 2024021340. https://doi.org/10.20944/preprints202402.1340.v1

Abstract

With the development of organizational biology and forced from the EU Cosmetic Regulation (EU/1223/2009) with the complete ban of animal testing for cosmetic purposes, 3D skin models have been widely developed due to their similar physiological structure and metabolic function to native human tissue. 3D skin models for in vitro cosmetic evaluation are still promising alternative methods for evaluating phototoxicity, corrosivity and irritation. These models have been used for early screening and later validation of toxicity and efficacy evaluation by many well-known cosmetic companies. 3D skin models have become an important tool in cosmetic evaluation research. This article reviews the development of 3D skin models and their application in cosmetic evaluation. An outlook on the current application and future technological development directions in the cosmetic field is also presented.

Keywords

3D skin model; Cosmetics; In vitro assessment; Efficacy evaluation

Subject

Chemistry and Materials Science, Biomaterials

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