Preprint Review Version 1 Preserved in Portico This version is not peer-reviewed

Understanding Drug-Induced Movement Disorders: Causes, Symptoms, and Treatment

Version 1 : Received: 21 February 2024 / Approved: 22 February 2024 / Online: 22 February 2024 (07:49:51 CET)

How to cite: R. Santos, E. Understanding Drug-Induced Movement Disorders: Causes, Symptoms, and Treatment. Preprints 2024, 2024021258. https://doi.org/10.20944/preprints202402.1258.v1 R. Santos, E. Understanding Drug-Induced Movement Disorders: Causes, Symptoms, and Treatment. Preprints 2024, 2024021258. https://doi.org/10.20944/preprints202402.1258.v1

Abstract

Drug-induced movement disorders (DIMDs) are a group of neurological conditions caused by the use of certain medications. These disorders can significantly impact a person's quality of life and are essential to recognize and manage. This article provides an overview of the causes, symptoms, and treatment of DIMDs. DIMDs can manifest in various forms, including parkinsonism, tardive dyskinesia, dystonia, and akathisia. They are most commonly associated with medications such as neuroleptics, antidepressants, antipsychotics, antiemetics, and anticonvulsants. Risk factors for developing DIMDs include age, genetics, duration of medication use, and dose of medication. Symptoms of DIMDs can range from mild to severe and may include tremors, rigidity, bradykinesia, and involuntary movements. These symptoms can significantly impact a person's ability to perform daily activities and lead to social isolation and decreased quality of life. DIMD diagnoses are based on clinical evaluation, including a thorough medical history and physical examination. Imaging studies such as MRI or CT scans may also be used to rule out other possible causes of symptoms. Treatment of DIMDs involves the withdrawal of the offending medication if possible. Pharmacological treatments such as anticholinergic drugs, benzodiazepines, and dopamine agonists may also be used to manage symptoms. Non-pharmacological treatments such as physical, occupational, and speech therapy can also be beneficial. DIMDs are necessary neurological conditions that can significantly impact a person's quality of life. Early recognition and management of these disorders are essential for optimizing outcomes. Further research is needed to understand the underlying mechanisms of DIMDs better and to develop more effective treatments.

Keywords

DIMD; DIP; Review; parkinsonism; DID; dyskinesia; tardive syndromes

Subject

Medicine and Pharmacology, Internal Medicine

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