Version 1
: Received: 9 February 2024 / Approved: 12 February 2024 / Online: 12 February 2024 (05:35:59 CET)
How to cite:
Ferrari, I. V. Evaluating Hypericin as a Therapeutic Agent Against Neisseria gonorrhoeae. Preprints2024, 2024020636. https://doi.org/10.20944/preprints202402.0636.v1
Ferrari, I. V. Evaluating Hypericin as a Therapeutic Agent Against Neisseria gonorrhoeae. Preprints 2024, 2024020636. https://doi.org/10.20944/preprints202402.0636.v1
Ferrari, I. V. Evaluating Hypericin as a Therapeutic Agent Against Neisseria gonorrhoeae. Preprints2024, 2024020636. https://doi.org/10.20944/preprints202402.0636.v1
APA Style
Ferrari, I. V. (2024). <strong> </strong> Evaluating Hypericin as a Therapeutic Agent Against <em>Neisseria gonorrhoeae</em>. Preprints. https://doi.org/10.20944/preprints202402.0636.v1
Chicago/Turabian Style
Ferrari, I. V. 2024 "<strong> </strong> Evaluating Hypericin as a Therapeutic Agent Against <em>Neisseria gonorrhoeae</em>" Preprints. https://doi.org/10.20944/preprints202402.0636.v1
Abstract
Neisseria gonorrhoeae is a bacterium that causes the sexually transmitted infection gonorrhea.This study employed molecular docking simulations to investigate potential interactions between natural molecules and the Fe(3+) ions import ATP-binding protein fbpC in Neisseria gonorrhoeae FA 1090. Among the screened molecules, Hypericin exhibited a remarkable binding energy of approximately -13.2 kcal/mol, indicating a robust and favorable binding affinity with the target protein. This promising outcome suggests that Hypericin could serve as a potential candidate for further exploration as a therapeutic agent against Neisseria gonorrhoeae infections. However, it is imperative to emphasize that these in silico findings necessitate experimental validation through in vitro and in vivo studies to ascertain the actual efficacy and safety of Hypericin as a treatment option.
Public Health and Healthcare, Public, Environmental and Occupational Health
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
