Preprint Article Version 1 Preserved in Portico This version is not peer-reviewed

Quantification and Influence by IL-1β of the Pain and Inflammatory Response after Placement of a Cement-Screw-Retained Restoration

Version 1 : Received: 9 February 2024 / Approved: 9 February 2024 / Online: 9 February 2024 (13:54:21 CET)

A peer-reviewed article of this Preprint also exists.

Arbelaez-Bonozo, L.; Maza-Solano, S.; Baus-Domínguez, M.; Gómez-Díaz, R.; Ruiz-de-Leon-Pacheco, G.; Torres-Lagares, D.; Serrera-Figallo, M.-A. Quantification and Influence of IL-1β on Pain and Inflammatory Response after Placement of a Cement–Screw-Retained Restoration. J. Clin. Med. 2024, 13, 1669. Arbelaez-Bonozo, L.; Maza-Solano, S.; Baus-Domínguez, M.; Gómez-Díaz, R.; Ruiz-de-Leon-Pacheco, G.; Torres-Lagares, D.; Serrera-Figallo, M.-A. Quantification and Influence of IL-1β on Pain and Inflammatory Response after Placement of a Cement–Screw-Retained Restoration. J. Clin. Med. 2024, 13, 1669.

Abstract

The objective of this study was to evaluate the pain and inflammatory response in soft tissues using healing and prosthetic abutments of different diameters and lengths. Methods: The study population was rehabilitated with Astra tech EV single implants (Dentsply Sirona, Atlantis, Dentsply Sirona S.A., Barcelona, Spain), 4.2 and 4.8 millimetres in diameter in upper and lower maxilla and loaded with custom abutments digitally designed with the software of the company Dentsply Sirona (Atlantis WebOrder, Dentsply Sirona S.A., Barcelona, Spain), version 4.6.5, with a larger diameter than the healing abutment, to account for biomarkers through ELISA. Results: Rehabilitations in mandible and with healing abutments below 4.29 millimetres and rehabilitators below 2.18 millimetres elicited higher pain and inflammatory responses, and in turn higher interleukin 1β values. Conclusions: Greater inflammation was evident in cases in which healing abutments with reduced diameter were used in relation to the same subsequent rehabilitation with prosthetic abutments of larger diameter.

Keywords

Screw-cemented retained implant prothesis; customised CAD-CAM abutments; peri-implant crevicular fluid; healing abutments; dental implants.

Subject

Medicine and Pharmacology, Dentistry and Oral Surgery

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