Preprint Article Version 1 Preserved in Portico This version is not peer-reviewed

Development of Chitosan Membrane Reinforced With Hydroxy-Apatite Derived From Pterygoplichthys spp (Armored Catfish)

Version 1 : Received: 8 February 2024 / Approved: 8 February 2024 / Online: 8 February 2024 (06:41:33 CET)

How to cite: Luna-Domínguez, J.H.; Mendoza-Martínez, A.M.; Câmara-Cozza, R.; Anzures-Mendoza, A.C. Development of Chitosan Membrane Reinforced With Hydroxy-Apatite Derived From Pterygoplichthys spp (Armored Catfish). Preprints 2024, 2024020494. https://doi.org/10.20944/preprints202402.0494.v1 Luna-Domínguez, J.H.; Mendoza-Martínez, A.M.; Câmara-Cozza, R.; Anzures-Mendoza, A.C. Development of Chitosan Membrane Reinforced With Hydroxy-Apatite Derived From Pterygoplichthys spp (Armored Catfish). Preprints 2024, 2024020494. https://doi.org/10.20944/preprints202402.0494.v1

Abstract

Abstract: Nowadays, there is an increasing interest in the development of novel bioresorbable membranes for Guided Bone Regeneration (GBR). Hydroxyapatite of different resources in com-bination with chitosan has been used successfully. In this work, armored catfish (Pterygoplich-thys spp) bone as a source of hydroxyapatite is proposed; it was isolated through bone calcina-tion at a temperature of 1000 °C. The hydroxyapatite obtained was analyzed for its chemical composition by means of Energy Dispersive Spectroscopy (EDS), its functional groups by Fouri-er Transform Infrared Spectroscopy (FT-IR), its crystallographic structures were analyzed by X-ray diffraction (DRX) and Scanning electron microscopy (SEM) was used to observe the mor-phology of the particle. The composed membrane presents a major roughness morphology sur-face than the pristine chitosan membrane. The hydroxyapatite particles added to the polymeric matrix increased the mechanical tensile properties of the membrane. These findings confirm that armored catfish bones are a viable, economic, and environmentally friendly source of hydroxy-apatite, which combined with chitosan, is a suitable alternative to develop biocompatible GBR membranes after it is combined with chitosan.

Keywords

Hydroxyapatite; armored catfish; chitosan membrane; tissue regeneration

Subject

Chemistry and Materials Science, Biomaterials

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